DRSC/TRiP Functional Genomics Resources

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Protein Alignment croc and FOXD4

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_997188.2 Gene:FOXD4 / 2298 HGNCID:3805 Length:439 Species:Homo sapiens


Alignment Length:420 Identity:130/420 - (30%)
Similarity:174/420 - (41%) Gaps:96/420 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 PYSASAYGLGAPHQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQ 115
            |.||:     |....::..|||.||||||.|||..:..|::||:||..:|.:||||||.....||
Human    90 PRSAA-----ASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQ 149

  Fly   116 NSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIK 180
            ||||||||||:||||:.|:..:||||:||:|||.|.:|||||||||||:||:            :
Human   150 NSIRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQ------------R 202

  Fly   181 RQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLA 245
            .|......|....||.            |||||.....|...||..:..:....|..|:      
Human   203 HQPTPGAHLPHPFPLP------------AAHAALHNPRPGPLLGAPAPPQPVPGAYPNT------ 249

  Fly   246 QMNHLAGGGVEHPGFTVDSLMNVYNPR---IHHSAY---PYHLNEDNLATVASSQMHHVHHA-AA 303
                       .||....:|::.:.||   :...||   |......:|||.|.......|.. :.
Human   250 -----------GPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSL 303

  Fly   304 AHHAQQLQRHVAHVA--HPLTPGGQGAGGQSSGHSPTTISTPHG---PAHGGWYTPETPPSEPVP 363
            ...|:..:||....|  ..|....:|:|.:..| .......|.|   |.........|...:...
Human   304 GRRARVWRRHREADASLSALRVSCKGSGERVQG-LRRVCPRPRGATAPCSSDRQACRTILQQQQR 367

  Fly   364 H------NGQQGTPTHP---GHNNNNSSSVLNHNGVGNGGG----GGGGGGGGSSSVLTSSPTSA 415
            |      ||  ..||..   |.:.:.:|::|.:..|..|.|    ....||.|:|.|...|||  
Human   368 HQEEDCANG--CAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPT-- 428

  Fly   416 LGFRDMIFEQNQSCQLDTGSPTGSLQSASP 445
                                |:...:||.|
Human   429 --------------------PSSLAESAGP 438

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 53/85 (62%)
FOXD4NP_997188.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..46
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 62..104 4/18 (22%)
Forkhead 104..189 CDD:306709 52/84 (62%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 203..232 10/40 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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