Protein Alignment croc and FOXF2

DIOPT Version :10

• Sequence 1: NP_524202.1
• Gene: croc / 40374
• FlyBaseID: FBgn0014143
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001443.1
• Gene: FOXF2 / 2295
• HGNCID: 3810
• Length: 444
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 144/508 - (28%)
• Similarity: 197/508 - (38%)
• Gaps: 167/508 - (32%)

  Fly     3 TLFSDQNSFTRHYAQTAAGYGSASAVAAASSASAAAAAHYAYDQYSRYPYSASAYGLGAPHQNKE 67
            |..|..:|.:...|.:::...||||.:||..::....|...    |.....||: ||..|.
Human    44 TTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAG----SGGAKKASS-GLRRPE---- 99

  Fly    68 IVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVA 132
              ||||||||||.||||::..|::||:.|||::..|||::|...|||:||:||||||||||:|:.
Human   100 --KPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLP 162

  Fly   133 RDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPL-K 196
            :...:||||.|||:||.|..||:.|||.||.|.|::                   |...:||: .
Human   163 KGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRR-------------------KCQALKPMYH 208

  Fly   197 LMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAGGGV-EHPGF 260
            .:.:|:.....:......|:..|...|||.|........|:.:.:|        ||.|. .|
Human   209 RVVSGLGFGASLLPQGFDFQAPPSAPLGCHSQGGYGGLDMMPAGYD--------AGAGAPSH--- 262

  Fly   261 TVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHPLTPGG 325
                            |:|:|                 ||    ||      ||.|::
Human   263 ----------------AHPHH-----------------HH----HH------HVPHMS------- 277

  Fly   326 QGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHNGQQGTPTHPGHNNNNSSSVLNHNGV 390
                                |..|..|....|            .|..||             ||
Human   278 --------------------PNPGSTYMASCP------------VPAGPG-------------GV 297

  Fly   391 GNGGGGGGG--GGGGSSSVLTSSPTSALGFRDMIFEQNQSCQLDTGSPTG--SLQSASP------ 445
            |..||||||  |...|||.:.|||..|...         .|.....||..  |...|||
Human   298 GAAGGGGGGDYGPDSSSSPVPSSPAMASAI---------ECHSPYTSPAAHWSSPGASPYLKQPP 353

  Fly   446 ---PASASVAAASAAAAAAVISSHHHHHHHHAALSGNLGQLGQLSNLSHYRPH 495
               |:|...|:|...::.:..|....:.|.:|....::|       |..|:.|
Human   354 ALTPSSNPAASAGLHSSMSSYSLEQSYLHQNAREDLSVG-------LPRYQHH 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	FH_FOX	69..159	CDD:469596	53/89 (60%)
FOXF2	NP_001443.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..98		16/58 (28%)
		FH_FOXF1	101..199	CDD:410823	58/116 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..323		36/164 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..367		8/28 (29%)