DRSC/TRiP Functional Genomics Resources

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Protein Alignment croc and FOXD4L1

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_036316.1 Gene:FOXD4L1 / 200350 HGNCID:18521 Length:408 Species:Homo sapiens


Alignment Length:464 Identity:132/464 - (28%)
Similarity:172/464 - (37%) Gaps:189/464 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 PYSASAYGLGAPHQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQ 115
            |.||:     |....::..||||||||||.|||..:..|::||:||..:|..||||||.....||
Human    93 PRSAA-----ASEDARQPAKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQ 152

  Fly   116 NSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIK 180
            ||||||||||:||||:.|:...||||:||:|||.|.:|||||||||||:|||:..          
Human   153 NSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQ---------- 207

  Fly   181 RQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLA 245
                             :|.|        ||..|  ..||         ..:|||:.|       
Human   208 -----------------LTPG--------AHLPH--PFPL---------PAAHAALHN------- 229

  Fly   246 QMNHLAGGGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQL 310
                      ..||           |.:...|.|..:..                          
Human   230 ----------PRPG-----------PLLGAPALPQPVPG-------------------------- 247

  Fly   311 QRHVAHVAHPLTPGGQGAGGQSSGHSPTTISTPH--------GPAHGGWYTPE--------TPPS 359
                   |:|.|         :.|..|..:..||        .||:.|  .|:        ||.:
Human   248 -------AYPNT---------APGRRPYALLHPHPPRYLLLSAPAYAG--APKKAEGADLATPGT 294

  Fly   360 EPV--PHNGQQGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRDMI 422
            .||  |..|.|  |...|            .|:.:..|||        .:..|..:...|.|   
Human   295 LPVLQPSLGPQ--PWEEG------------KGLASPPGGG--------CISFSIESIMQGVR--- 334

  Fly   423 FEQNQSCQLDTGSPTGSLQSASP-----------PASAS-VAAASAAAAAAVISSHHHHHHHHAA 475
                       |:.||:.||.||           |:|.| ..||:|||:...:......|....|
Human   335 -----------GAGTGAAQSLSPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGA 388

  Fly   476 LSGNLGQLG 484
            ....:|::|
Human   389 GRAPVGRVG 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 54/85 (64%)
FOXD4L1NP_036316.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..54
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..104 4/15 (27%)
Forkhead 107..193 CDD:278670 54/85 (64%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 385..408 3/13 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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