DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment croc and unc-130

DIOPT Version :9

Sequence 1:	NP_524202.1	Gene:	croc / 40374	FlyBaseID:	FBgn0014143	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_496411.1	Gene:	unc-130 / 174721	WormBaseID:	WBGene00006853	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	144	Identity:	75/144 - (52%)
Similarity:	97/144 - (67%)	Gaps:	8/144 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 ASAVAAASSASAAAAAHYAYDQYSRYPYSASAYGLGAPHQNKEIVKPPYSYIALIAMAIQNAADK 89
            :::.||.||:..|.......|..||...|.        |:.....||||||||||||:|.|:.:|
Worm    90 STSSAADSSSDDAKDDDDDDDSTSRKSMSG--------HRKSSHAKPPYSYIALIAMSILNSPEK 146

  Fly    90 KVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMF 154
            |:||:.|.::|:.:|.||::....||||||||||||:|||||||....||||:||.|||:..:||
Worm   147 KLTLSEICEFIINKFEYYKEKFPAWQNSIRHNLSLNDCFVKVARGPGNPGKGNYWALDPNCEDMF 211

  Fly   155 DNGSFLRRRRRFKK 168
            |||||||||:|:||
Worm   212 DNGSFLRRRKRYKK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	Forkhead	70..156	CDD:278670	53/85 (62%)
unc-130	NP_496411.1	COG5025	<126..330	CDD:227358	65/100 (65%)
unc-130	NP_496411.1	Forkhead	127..212	CDD:365978	52/84 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820