Protein Alignment croc and Foxa2

DIOPT Version :10

• Sequence 1: NP_524202.1
• Gene: croc / 40374
• FlyBaseID: FBgn0014143
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001277994.1
• Gene: Foxa2 / 15376
• MGIID: 1347476
• Length: 465
• Species: Mus musculus
• Alignment Length: 388
• Identity: 129/388 - (33%)
• Similarity: 170/388 - (43%)
• Gaps: 98/388 - (25%)

  Fly    20 AGYGSASAVAAASSASAAAAA------HYAYDQYSRYPYSASAYGLGAPHQNKEIV--------- 69
            ||....:...|..|.||.||.      |.:.........:|.|.|..||:.|...:
Mouse    84 AGMSPGAGAMAGMSGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANMNSMSPMYGQAGL 148

  Fly    70 ----------------KPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSI 118
                            |||||||:||.||||.:.:|.:||:.|||:||:.||:||.|:|.|||||
Mouse   149 SRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSI 213

  Fly   119 RHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKR-- 181
            ||:||.|:||:||.|...||||||:|||.|||.|||:||.:|||::|||     .||:.|:|.
Mouse   214 RHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK-----CEKQLALKEAA 273

  Fly   182 -----------------QAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGK 229
                             ||.:.|...........|    |:.|.:|......|.     |.||..
Mouse   274 GAASSGGKKTAPGSQASQAQLGEAAGSASETPAGT----ESPHSSASPCQEHKR-----GGLSEL 329

  Fly   230 EVSHAAMLNSCH--DSLAQMNHLAG---GGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLAT 289
            :.:.|:.|:...  .|..|....|.   |...|||...::.:   .|. ||.|:.:..:.:||
Mouse   330 KGAPASALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHL---KPE-HHYAFNHPFSINNL-- 388

  Fly   290 VASSQMHHVHHAAAAHHAQ------QLQRHVAHVAHPLTPGGQGAGGQSSGHSPTTISTPHGP 346
            ::|.|.||..|    ||.|      :....|.|.     |||.|        ||...|...||
Mouse   389 MSSEQQHHHSH----HHHQPHKMDLKAYEQVMHY-----PGGYG--------SPMPGSLAMGP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	FH_FOX	69..159	CDD:469596	59/114 (52%)
Foxa2	NP_001277994.1	Forkhead_N	23..164	CDD:369872	15/79 (19%)
		FH_FOXA2	163..264	CDD:410813	65/105 (62%)
		PRK07764	<266..>354	CDD:236090	17/96 (18%)
		HNF_C	380..454	CDD:430552	21/74 (28%)