DRSC/TRiP Functional Genomics Resources

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Protein Alignment croc and Foxg1

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_001153584.1 Gene:Foxg1 / 15228 MGIID:1347464 Length:481 Species:Mus musculus


Alignment Length:357 Identity:115/357 - (32%)
Similarity:154/357 - (43%) Gaps:84/357 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 QNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECF 128
            :|.:..|||:||.|||.|||:.:.:|::||||||::||:.|||||:||||||||||||||||:||
Mouse   167 KNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCF 231

  Fly   129 VKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMK 193
            |||.|....||||:||.|||.|.::|..|:..:.||                |......|||..:
Mouse   232 VKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRR----------------RSTTSRAKLAFKR 280

  Fly   194 PLKLMTNGILEAKHMAAHAAHFKKEPLMDL------GCLSGKEVSHAAMLNSC-HDSLAQMNHLA 251
            ..:|.:.|:.....  |.:.::...|.:.|      ..||....:.|...:.. :.|:...|.| 
Mouse   281 GARLTSTGLTFMDR--AGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSL- 342

  Fly   252 GGGVEHP-----GFTVDSLMNVYNPRIHHSAYPYHLNEDNLA-------TVASSQMHHVHHAAAA 304
              |..|.     |.:||.|:|...|...|     ||....||       :|..|..:.::..:..
Mouse   343 --GNNHSFSTANGLSVDRLVNGEIPYATH-----HLTAAALAASVPCGLSVPCSGTYSLNPCSVN 400

  Fly   305 HHAQQLQRHVAHVAHP----LTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHN 365
            ..|.|......||.||    .|.....|...||..||              ..|.|.|.|.:   
Mouse   401 LLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSP--------------QAPSTLPCESL--- 448

  Fly   366 GQQGTPTHPG--------------HNNNNSSS 383
                .|:.|.              |.|..|||
Mouse   449 ----RPSLPSFTTGLSGGLSDYFTHQNQGSSS 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 58/85 (68%)
Foxg1NP_001153584.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 31..173 1/5 (20%)
FH 173..261 CDD:214627 58/87 (67%)
Required for interaction with TLE6. /evidence=ECO:0000269|PubMed:16314515 241..336 26/112 (23%)
Interaction with KDM5B. /evidence=ECO:0000250 375..398 4/22 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 419..447 9/41 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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