DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment croc and Foxj1

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_032266.3 Gene:Foxj1 / 15223 MGIID:1347474 Length:421 Species:Mus musculus


Alignment Length:384 Identity:98/384 - (25%)
Similarity:141/384 - (36%) Gaps:129/384 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 GYGSASAVAAASSASAAAAAHYAYDQYSRYPYS-----ASAYGLGAP------HQNKEIVKPPYS 74
            ||.....:.|..|..||..|..........|.|     ::..||.||      :.....||||||
Mouse    61 GYHQVPGLVAPGSPLAADPACLGQPHTPGKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYS 125

  Fly    75 YIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPG 139
            |..||.||:|.:...|:||:.||::|.:.|.|:|.....||||||||||||:||:||.|:..:||
Mouse   126 YATLICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPG 190

  Fly   140 KGSYWTLDPDSYNMFDNGSFLRRR-----------RRFKK-----------------KDVMREKE 176
            ||.:|.:||.......:|:|.:||           |:..:                 :.:::|.|
Mouse   191 KGGFWRIDPQYAERLLSGAFKKRRLPPVHIHPAFARQASQEPSAAPWGGPLTVNREAQQLLQEFE 255

  Fly   177 EAI---------------------KRQA----------MMNEKLAEMKPLKLMTNGILEAKHMAA 210
            ||.                     ||.|          :..|:..|::|||              
Mouse   256 EATGEGGWGTGEGRLGHKRKQPLPKRVAKVLRPPSTLLLTQEEQGELEPLK-------------- 306

  Fly   211 HAAHFKKEPLMDLGCLSGKEVSHAAMLN-------SCHDSLAQMNHLAGGGVEHPGFTVDSLMNV 268
              .:|..|.:.:.|.| |:|:|....|.       |.|..:....|  |..:..|.        .
Mouse   307 --GNFDWEAIFEAGAL-GEELSSLEGLELSPPLSPSSHGDVDLTVH--GRHINCPA--------T 358

  Fly   269 YNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHPLTPGGQG 327
            :.|....:|.....:|..|||                         :.:.||....|.|
Mouse   359 WGPPAEQAADSLDFDETFLAT-------------------------SFLQHPWDESGSG 392

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 44/85 (52%)
Foxj1NP_032266.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..32
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 77..110 8/32 (25%)
Forkhead 121..205 CDD:365978 44/83 (53%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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