DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment croc and Foxl1

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_032050.2 Gene:Foxl1 / 14241 MGIID:1347469 Length:336 Species:Mus musculus


Alignment Length:335 Identity:119/335 - (35%)
Similarity:155/335 - (46%) Gaps:68/335 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 SASAAAAAHYAYD-QYSRYPYS-ASAYGLGAPHQNKEIVKPPYSYIALIAMAIQNAADKKVTLNG 95
            :|.||:...|.|. :....|.: |.|..|..|.:.:...|||||||||||||||:|.:::|||||
Mouse    10 AALAASPLLYVYSPERPGLPLAFAPAAALAGPGRVEPPQKPPYSYIALIAMAIQDAPEQRVTLNG 74

  Fly    96 IYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFL 160
            |||:||:|||:|.||:||||||||||||||||||||.|:..:|||||||||||...:||:||::.
Mouse    75 IYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYR 139

  Fly   161 RRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGC 225
            ||:|:                          .||    ..|..|||....      :.|..::||
Mouse   140 RRKRK--------------------------PKP----AAGSPEAKRTRV------EPPESEVGC 168

  Fly   226 LSGKEVSHAAMLNSCHDSLAQMNHLAGGGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATV 290
            ..|......|:                 ....|..:....:....|.:.....|...:.|...||
Mouse   169 DVGSPDLATAL-----------------PTRAPDRSQSPAVGTARPALLPWPGPEPRDPDADLTV 216

  Fly   291 ASSQMHHVHHAAAAHHAQQLQRHVAHVAHPLTPGGQGA--GGQSSGHSPTTISTPHGPAHGGWYT 353
                     ..|.|..:.||||...|:..||.|...|:  |.:|...|..:|.........|...
Mouse   217 ---------QGAGAVASGQLQRPAHHLGSPLCPAPSGSPKGSKSKSFSIDSILAVRPTPASGAEA 272

  Fly   354 PETPPSEPVP 363
            |..|  :|||
Mouse   273 PGIP--KPVP 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 66/85 (78%)
Foxl1NP_032050.2 FH 49..137 CDD:214627 67/87 (77%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 140..214 18/126 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 227..252 9/24 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11829
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.920

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