DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment croc and Foxs1

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_034356.1 Gene:Foxs1 / 14239 MGIID:95546 Length:329 Species:Mus musculus


Alignment Length:325 Identity:121/325 - (37%)
Similarity:162/325 - (49%) Gaps:54/325 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 APHQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLN 125
            ||  :.|..|||||||||||||||::..::.||:|||:|||.||.:||.|:.|||||||||||||
Mouse    11 AP--SAEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLN 73

  Fly   126 ECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIK---------- 180
            ||||||.|||:|||||||||||||.::||.:||||||||||.|:...:..:..:|          
Mouse    74 ECFVKVPRDDRKPGKGSYWTLDPDCHDMFQHGSFLRRRRRFTKRTGAQGTKGPVKIDHRPHRATS 138

  Fly   181 -----------RQAMMNEKLAEMKPLK---LMTNGILEAKHMAAHAAHFKKE----PLMDLGCLS 227
                       |.....:::...|.|.   ||  |.|.| :|::..:..:.:    |.......|
Mouse   139 PDPGAPKTTTGRLCPFPQEVPNPKGLSFEGLM--GSLPA-NMSSTTSDVRPQLPTGPKEMCSAKS 200

  Fly   228 G--KEVSHAAMLNSC-----HDSLAQMNHLAGGGVEHPGFTVDSLMNVYNPRIHHSAYPY----- 280
            |  :|:|.|...:.|     ..:.:....|  |....||...:|:.:.|..|:....:..     
Mouse   201 GGPRELSEATSPSPCPAFGFSSAFSDAESL--GKAPTPGVAPESVGSSYQCRMQTLNFCMGTDPG 263

  Fly   281 --HLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHPLTPGGQGAGGQSSGHSPTTISTP 343
              ||...::.|..||.....|.|.....|...:..||. :.|:    ||..|...|..|....||
Mouse   264 LEHLLVSSVPTPGSSTPSASHRAPLPLPADSKEPWVAG-SFPV----QGGSGYPLGLPPCLYRTP 323

  Fly   344  343
            Mouse   324  323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 65/85 (76%)
Foxs1NP_034356.1 Forkhead 18..103 CDD:278670 64/84 (76%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 117..150 1/32 (3%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 174..213 8/39 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11829
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.910

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