DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment croc and foxf2b

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:XP_003200754.1 Gene:foxf2b / 100002904 ZFINID:ZDB-GENE-041001-130 Length:429 Species:Danio rerio


Alignment Length:525 Identity:133/525 - (25%)
Similarity:186/525 - (35%) Gaps:197/525 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 FSDQNSF----TRHYAQTAAGYGSASAVAAASSASAAAAAHYA-------YDQYSRYPYSASA-Y 57
            ||..|..    |.....|.:.:|...:.....::.|..|.|..       .:::|....|... .
Zfish    40 FSSDNGLFSYVTAGPMTTESSHGPLGSTPPTRTSPATTALHPGLMNSTGNLEEHSAVSKSKKTNS 104

  Fly    58 GLGAPHQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNL 122
            ||..|.      ||||||||||.||||:|..|::||:.|||::..|||::|.:.|||:||:||||
Zfish   105 GLRRPE------KPPYSYIALIVMAIQSAPTKRLTLSEIYQFLQTRFPFFRGSYQGWKNSVRHNL 163

  Fly   123 SLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNE 187
            ||||||:|:.:...:||||.|||:||.|..||:.|||.||.|.|::                   
Zfish   164 SLNECFIKLPKGLGRPGKGHYWTIDPTSEFMFEEGSFRRRPRGFRR------------------- 209

  Fly   188 KLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAG 252
            |...|||:..|.||                   :..|         :|:|....|..:....|| 
Zfish   210 KCQAMKPMYRMMNG-------------------LGFG---------SAILPQSFDYQSPTGALA- 245

  Fly   253 GGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQ-------- 309
                                .|.|.|...|:.....:::|.  ||.|.:.::.|...        
Zfish   246 --------------------CHSSGYNLDLSGSGYESISSG--HHGHMSPSSRHGYMSSCPMPGN 288

  Fly   310 ----LQRHVAHVAHPLTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPE----TPPSEPV-PHN 365
                ::.:.:.|     |......|...||||.:.||....:....|..:    |..|:|. .|.
Zfish   289 GDYAVESNTSPV-----PSSPAVAGALEGHSPYSESTALWASSNSSYLKQANTITSNSQPTGQHP 348

  Fly   366 G------QQG------------------TPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSS 406
            |      :||                  .|||..........:||.||:                
Zfish   349 GIFTYSLEQGYIQQSARDNADMSVGLSRYPTHSSPVGERKDFMLNFNGI---------------- 397

  Fly   407 VLTSSPTSALGFRDMIFEQNQSCQLDTGSPTGSLQSASPPASASVAAASAAAAAAVISSHHHHHH 471
              ||...||.|:                                             ..||||||
Zfish   398 --TSFHPSAGGY---------------------------------------------YHHHHHHH 415

  Fly   472 HHAAL 476
            ||.::
Zfish   416 HHQSM 420

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 53/85 (62%)
foxf2bXP_003200754.1 FH 111..199 CDD:214627 53/87 (61%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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