Protein Alignment Syx6 and STX8

DIOPT Version :9

• Sequence 1: NP_995816.1
• Gene: Syx6 / 40373
• FlyBaseID: FBgn0037084
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_004844.1
• Gene: STX8 / 9482
• HGNCID: 11443
• Length: 236
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 62/255 - (24%)
• Similarity: 100/255 - (39%)
• Gaps: 60/255 - (23%)

  Fly    84 EKNPSKFRIDNRELSSRRHFIDNTRDEVKQMKDKMSLNRSRDRDITAHQ-PLLDNDRHSPNHNHS 147
            ||.| |..:..|.|      :.|.::::..:||.:.      |.::.|| ..|:.||
Human    35 EKAP-KLTVTIRAL------LQNLKEKIALLKDLLL------RAVSTHQITQLEGDR-------- 78

  Fly   148 IAIPNSNSNSNEYHQHPHNDRTYLVECPNGNSLINSGSQVANTIAGTMSAAAAAASRHSGTKYSK 212
                    ..|........:|..|.      |..|.|::.....:..||..|...:.:..
Human    79 --------RQNLLDDLVTRERLLLA------SFKNEGAEPDLIRSSLMSEEAKRGAPNPW----- 124

  Fly   213 LENALDSPSHYGQTHHGGMDSPSHRYVGETVSIQQRMIQGQDEQLDMISDSIGTLKTVSRQIGVE 277
               ..:.|.   :|...|.|        |....||::||.||..||.:|..|...|.:.::||.|
Human   125 ---LFEEPE---ETRGLGFD--------EIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNE 175

  Fly   278 LDEQAVMLDDFGNEFDTTESKLDTTMKKVAKVLHMNNDKRQWAAILILSGLLLFVIILFI 337
            ||||..::||..|..:.|:.||....::|..|     |::..:..:|:..|||.|.|:.:
Human   176 LDEQNEIIDDLANLVENTDEKLRNETRRVNMV-----DRKSASCGMIMVILLLLVAIVVV 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx6	NP_995816.1	Syntaxin-6_N	29..115	CDD:286286	7/30 (23%)
		SNARE_Syntaxin6	250..315	CDD:277204	24/64 (38%)
STX8	NP_004844.1	SNARE_Syntaxin8	152..204	CDD:277205	19/51 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154217
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740