DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx6 and stx6

DIOPT Version :9

Sequence 1:	NP_995816.1	Gene:	Syx6 / 40373	FlyBaseID:	FBgn0037084	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001039240.1	Gene:	stx6 / 734102	XenbaseID:	XB-GENE-1015934	Length:	254	Species:	Xenopus tropicalis

Alignment Length:	322	Identity:	123/322 - (38%)
Similarity:	170/322 - (52%)	Gaps:	79/322 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PF--PNSEVFKALNKTRGLYLRWRELGENGG----TEAEWTTTELRNSLRSIEWDLEDLEDTISI 82
            ||  ...||.||:|..:||:.||.:|.::..    .|.:|||.||||:|||||||||||::||||
Frog     6 PFFVVRGEVQKAVNTAQGLFQRWTDLLQDPSISTREELDWTTNELRNNLRSIEWDLEDLDETISI 70

  Fly    83 VEKNPSKFRIDNRELSSRRHFIDNTRDEVKQMKDKMSLNRSRDRDITAHQPLLDNDRHSPNHNHS 147
            ||.||.||.:|..||..|:.||..||..||.|||:|:                     ||:..
Frog    71 VESNPRKFSLDPAELRQRKAFISETRQCVKDMKDRMT---------------------SPSVQ-- 112

  Fly   148 IAIPNSNSNSNEYHQHPHNDRTYLVECPNGNSLINSGSQVANTIAGTMSAAAAAASRHSGTKYSK 212
                                  .|.|..|..:|:..|                  ::|.....::
Frog   113 ----------------------ALTEKKNRQALLGEG------------------TKHGWNLETE 137

  Fly   213 LENALDSPSHYGQTHHGGMDSPSHRYVGETVSIQQRMIQGQDEQLDMISDSIGTLKTVSRQIGVE 277
            ...|||..          :::.:.:::...|..||.:::.|||||:::|.|||.||.:|::||.|
Frog   138 KYKALDQE----------LENANSQFLDGQVGQQQLIMEQQDEQLELVSGSIGVLKNMSQRIGSE 192

  Fly   278 LDEQAVMLDDFGNEFDTTESKLDTTMKKVAKVLHMNNDKRQWAAILILSGLLLFVIILFIIL 339
            |||||||||||.:|.||.:|::|..:||:|||.||.:|:|||.||:||..|||.|:|||..|
Frog   193 LDEQAVMLDDFSHELDTAQSRMDNVLKKLAKVSHMTSDRRQWCAIIILLSLLLVVLILFFAL 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx6	NP_995816.1	Syntaxin-6_N	29..115	CDD:286286	49/89 (55%)
Syx6	NP_995816.1	SNARE_Syntaxin6	250..315	CDD:277204	38/64 (59%)
stx6	NP_001039240.1	Syntaxin-6_N	13..103	CDD:286286	49/89 (55%)
stx6	NP_001039240.1	SNARE_Syntaxin6	165..230	CDD:277204	38/64 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I6972
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H115622
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4050
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1563292at2759
OrthoFinder	1	1.000	-	-		FOG0003084
OrthoInspector	1	1.000	-	-		otm49465
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3993
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060