DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alp1 and Akp3

DIOPT Version :9

Sequence 1:	NP_001262159.1	Gene:	Alp1 / 40372	FlyBaseID:	FBgn0283479	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_073171.2	Gene:	Akp3 / 64621	RGDID:	621650	Length:	558	Species:	Rattus norvegicus

Alignment Length:	500	Identity:	213/500 - (42%)
Similarity:	281/500 - (56%)	Gaps:	34/500 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 ELKSKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNRL 100
            |.::..||...|...|.......|.|..|||:|.||||||.||||||.||..|||.|.:|....|
  Rat    24 EEENPAFWNQKAADALNVAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGNLGPETPL 88

  Fly   101 EFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTADVELNDCRGSRLPQNRLSSI 165
            ..:.|.|:.|||||.|::||.|||.||:|||.|:|.||.||||:|....:.|..:.  .|.:.|:
  Rat    89 AMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTF--GNEVLSV 151

  Fly   166 AAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGNCPDIAQQLIDGDVG 230
            ...|.|..||.|:||||||.||||||.|.||.||::..|.|:.......| |.|||.||:.   .
  Rat   152 MYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADMPASALQEG-CKDIATQLVS---N 212

  Fly   231 KRLRVVMGGGTIKFL-------PNTTNDVFGNKGQRLDNRNLIEEWQQTKPGNARVVFSRTDLLN 288
            ..:.|::|||. |::       |...||| ...|.|||.:||::||.....| ::.|::|.:|:.
  Rat   213 MDINVILGGGR-KYMFPAGTPDPEYPNDV-NETGTRLDGKNLVQEWLSKHQG-SQYVWNRQELIQ 274

  Fly   289 NDAQ-NTDFLLGLFNASHLAYHMD-DSIDTPTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHAHH 351
            .... :..:|:|||......:.:. |.:..|:|.:||.||::||||:|.|::|||||||||..||
  Rat   275 KSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNPKGFYLFVEGGRIDRGHH 339

  Fly   352 ETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVD 416
            ...|..||.|.|.|..|:.:|.|||:..|||.:|:|||.|..:..||.....||.|| :.|:.:|
  Rat   340 LGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYTLRGTSIFGL-APLNALD 403

  Fly   417 QLPYTSISYANGPAYERFYKSTDGVVERVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYAHV 481
            ..|||||.|.|||.|.       |..||.::.:.:...|.......||:..|||||.|||::|
  Rat   404 GKPYTSILYGNGPGYV-------GTGERPNVTDAESHDPSYQQQAAVPVKSETHGGEDVAIFA-- 459

  Fly   482 VEYLLQGPWSHLFTGVYEQSTLPHLMGFASCLGPGITYCDLQPKA 526
                 :||.:||..||.||:.:.|:|.||.||.| .|.|.|.|.|
  Rat   460 -----RGPQAHLLHGVQEQNYIAHVMAFAGCLEP-YTDCGLAPPA 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp1	NP_001262159.1	alkPPc	65..514	CDD:214515	198/457 (43%)
Akp3	NP_073171.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351425
Domainoid	1	1.000	373	1.000	Domainoid score	I856
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm8918
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.860