Protein Alignment Alp1 and Alpl

DIOPT Version :9

• Sequence 1: NP_001262159.1
• Gene: Alp1 / 40372
• FlyBaseID: FBgn0283479
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001274101.1
• Gene: Alpl / 11647
• MGIID: 87983
• Length: 524
• Species: Mus musculus
• Alignment Length: 520
• Identity: 223/520 - (42%)
• Similarity: 302/520 - (58%)
• Gaps: 37/520 - (7%)

  Fly    10 LALQLTACSSQYKYGPEQSWDLDSISELKSKEFWFHDAQRTLYNKLSTPP-NQYRAKNVIFFLGD 73
            |.|.:..|.:. .:.||:..|         ..:|...||.||.|.|.... |...|||||.||||
Mouse     6 LVLAIGTCLTN-SFVPEKERD---------PSYWRQQAQETLKNALKLQKLNTNVAKNVIMFLGD 60

  Fly    74 GMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANY 138
            ||.|.||||.||..|||....||..|||.:||.:|.|||||..|.||.|||.||:|||.|:|||.
Mouse    61 GMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANE 125

  Fly   139 LTIGVTADVELNDCRGSRLPQNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFES 203
            .|:||:|..|...|..::  .|.::||..||....||.|:||||||.||:|:..|||:::||:.|
Mouse   126 GTVGVSAATERTRCNTTQ--GNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYS 188

  Fly   204 DYDVTKLGQNPGNCPDIAQQLIDGDVGKRLRVVMGGGTIKFLPNTTNDVFGN-----KGQRLDNR 263
            |.::.....:.| |.|||.||:...  |.:.|:||||.....|....||...     :|.|||..
Mouse   189 DNEMPPEALSQG-CKDIAYQLMHNI--KDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGL 250

  Fly   264 NLIEEWQQTKP--GNARVVFSRTDLLNNDAQNTDFLLGLFNASHLAYHMD-DSIDTPTLPEMTAA 325
            :||..|:..||  .::..|::||:||..|....|:|||||....:.|.:: :::..|:|.||...
Mouse   251 DLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEV 315

  Fly   326 AINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHG 390
            |:.:|:::..|:||.||||||||.|||.|||:||.|.|:...|:.||..:|:..|||.||:|||.
Mouse   316 ALRILTKNLKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGKAGAMTSQKDTLTVVTADHS 380

  Fly   391 HTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYKSTDGVVERVDLRNLDFSKP 455
            |..|..||....|||.||...:|:.|:.|:|:|.|.|||.    ||..||  ||.::..:|::..
Mouse   381 HVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPG----YKVVDG--ERENVSMVDYAHN 439

  Fly   456 DAIYPHGVPMTEETHGGGDVAVYAHVVEYLLQGPWSHLFTGVYEQSTLPHLMGFASCLGPGITYC 520
            :......||:..|||||.||||:|       :||.:||..||:||:.:||:|.:|||:|..:.:|
Mouse   440 NYQAQSAVPLRHETHGGEDVAVFA-------KGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHC 497

  Fly   521  520
            Mouse   498  497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp1	NP_001262159.1	alkPPc	65..514	CDD:214515	206/456 (45%)
Alpl	NP_001274101.1	Alk_phosphatase	51..490	CDD:333956	206/456 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847887
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm8903
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R959
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.790