Protein Alignment Alp1 and alpi.2

DIOPT Version :10

• Sequence 1: NP_001262159.1
• Gene: Alp1 / 40372
• FlyBaseID: FBgn0283479
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001116946.1
• Gene: alpi.2 / 100144722
• XenbaseID: XB-GENE-854953
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 525
• Identity: 219/525 - (41%)
• Similarity: 301/525 - (57%)
• Gaps: 38/525 - (7%)

  Fly     8 AALALQLTACSSQYKYGPEQSWDLDSISELKSKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLG 72
            |..||.|.|.:..    |.....:.|:...|:.:||...|:.||.|.|:..|..:||||:|.|||
 Frog    14 AVTALLLLAITVH----PSTGVVVSSLEAEKNPKFWNDQAKETLKNALNLNPITHRAKNLIMFLG 74

  Fly    73 DGMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKAN 137
            |||.|.|:.|.||:.||:.|..||.|.:..|||.||.|||.|.|:.||.|||.|.:|||.|:|||
 Frog    75 DGMGVTTIAAARIYQGQVEGQPGEENIMAMEKFPYVALSKVYNVDAQVPDSAGTGTAYLCGVKAN 139

  Fly   138 YLTIGVTADVELNDCRGSRLPQNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFE 202
            ..|:||:|.....:|..|:  .|.::||...|....||.|:||||||.||||...|||:::|::.
 Frog   140 SGTLGVSAAAIYGNCVSSK--GNEVTSILHRAKLAGKSVGIVTTTRVQHASPGAAYAHSASRNWY 202

  Fly   203 SDYDVTKLGQNPGNCPDIAQQLI-DGDVGKRLRVVMGGGTIKFLPNTTND-----VFGNKGQRLD 261
            ||.::|....|.| |.|||.||: :.|:.    |::|||.....|..|.|     ...::|.|.|
 Frog   203 SDNEMTSAMINNG-CKDIAYQLVHNTDID----VILGGGRAYMYPAGTPDPEYPGSSADRGLRRD 262

  Fly   262 NRNLIEEWQQTKPGNARVVFSRTDLLNNDAQNTDFLLGLFNASHLAYHM--DDSIDTPTLPEMTA 324
            ..||.:.| .:|..|||.|:::......:...||:|:|||....:.|.:  :.|:| |:|.|||.
 Frog   263 GLNLTDIW-LSKRQNARYVWNKEQFNAVNVDTTDYLMGLFEPKDMKYELNRNASLD-PSLAEMTE 325

  Fly   325 AAINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADH 389
            .||.:||::|.|:|||||||||||.||:..||::|.|.::|..||.:..|||...:||.||:|||
 Frog   326 KAIRILSKNPKGFFLFVEGGRIDHGHHDGNAKQSLTEALEFDKAVLRGGQLTQENETLTVVTADH 390

  Fly   390 GHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYKSTDGVVERVDLRNLDFSK 454
            .|..|..||.|..|||.||...|:: |:.||||:.|.|||.    |...|.:  |.::..::...
 Frog   391 SHVFTFGGYTDRGNSIFGLAPSLAS-DRKPYTSLLYGNGPG----YPLPDAI--RANITGVNTGS 448

  Fly   455 PDAIYPHGVPMTEETHGGGDVAVYAHVVEYLLQGPWSHLFTGVYEQSTLPHLMGFASCLGPGITY 519
            ...:....||:..|||||.|||:.|       :||.:|||.|.:|||.:.|:|.:|:||.|   |
 Frog   449 NSYLQQAAVPVVSETHGGEDVAIMA-------KGPQAHLFHGFHEQSYIAHVMAYAACLEP---Y 503

  Fly   520 CDLQP 524
            .:..|
 Frog   504 TECPP 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp1	NP_001262159.1	alkPPc	65..514	CDD:214515	197/456 (43%)
alpi.2	NP_001116946.1	Alk_phosphatase	66..500	CDD:395188	197/456 (43%)