DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aef1 and odd

DIOPT Version :9

Sequence 1:	NP_001262157.1	Gene:	Aef1 / 40370	FlyBaseID:	FBgn0005694	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	367	Identity:	110/367 - (29%)
Similarity:	151/367 - (41%)	Gaps:	82/367 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DIVIVAAQPQTTIA-----NNNNNETVTQATHPA-------------HMAAVQQQQQQQQQQQQQ 68
            |.:::..:.:|:::     .:...|...:..|||             |||..||||||||||||.
  Fly    30 DFIVIKEERETSLSPMLTPPHTPTEEPLRRVHPAISEEAVATQLHMRHMAHYQQQQQQQQQQQQH 94

  Fly    69 ----HHQQQQQQSSGPPSVPPPPTELPLPFQMHLSGISAEAHSAAQAAAMAAAQAAAAQAAAAEQ 129
                ..||||||...|...|..||....|..:|...::....:||              ....:|
  Fly    95 RLWLQMQQQQQQHQAPQQYPVYPTASADPVAVHQQLMNHWIRNAA--------------IYQQQQ 145

  Fly   130 QQPPPPTSHLTHLTTHSPTTIHSEH---YLANGHSEHPGEGNAAV--------------GVGGA- 176
            ||...|..|..|...|.|.. |..|   |.|..||.|     |||              |.|||
  Fly   146 QQQQHPHHHHHHGHPHHPHP-HPHHVRPYPAGLHSLH-----AAVMGRHFGAMPTLKLGGAGGAS 204

  Fly   177 --------VREPEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKI 233
                    ...|:|.|.|..|:|:|.:...|..|.:.||.|:||.|::|.|.||:...|.:|..|
  Fly   205 GVPSGATGSSRPKKQFICKYCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYI 269

  Fly   234 HTGEKPYNCNFCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVP 298
            |:.:||:.|:.|.|.|.|..|||.|...|..|.|.:|.||::.|.|.:.|.:|::.|
  Fly   270 HSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKCPICQRSFNQRANLKSHLQSH-------- 326

  Fly   299 VKIKTEED--EGXLGRMPLAAHHHQQQQHQHHHQQQQHQHHP 338
                :|:.  |. :...|..:|....|.......:...||.|
  Fly   327 ----SEQSTKEVVVTTSPATSHSVPNQALSSPQPENLAQHLP 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aef1	NP_001262157.1	C2H2 Zn finger	186..206	CDD:275368	6/19 (32%)
		zf-H2C2_2	199..223	CDD:290200	11/23 (48%)
		C2H2 Zn finger	214..234	CDD:275368	7/19 (37%)
		zf-H2C2_2	227..251	CDD:290200	10/23 (43%)
		C2H2 Zn finger	242..262	CDD:275368	9/19 (47%)
		zf-H2C2_2	255..279	CDD:290200	10/23 (43%)
		C2H2 Zn finger	270..290	CDD:275368	7/19 (37%)
odd	NP_722922.1	COG5048	<203..334	CDD:227381	47/142 (33%)
		C2H2 Zn finger	222..242	CDD:275368	6/19 (32%)
		zf-H2C2_2	234..259	CDD:290200	11/24 (46%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		zf-H2C2_2	262..285	CDD:290200	9/22 (41%)
		C2H2 Zn finger	278..298	CDD:275368	9/19 (47%)
		zf-C2H2	304..326	CDD:278523	7/21 (33%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960