DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aef1 and Opbp

DIOPT Version :9

Sequence 1:	NP_001262157.1	Gene:	Aef1 / 40370	FlyBaseID:	FBgn0005694	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster

Alignment Length:	380	Identity:	89/380 - (23%)
Similarity:	148/380 - (38%)	Gaps:	102/380 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 HHQQQQQQSSG-PPSVPPPPTELPLPFQMHLSGISAEAHSAAQAAAMAAAQAAAAQAAAAEQQQP 132
            |.|..||:||. ..|:.....|..:.:|||     .:.|...:.   :.:....||..:.::::|
  Fly   241 HKQMHQQESSEIMCSICNRKFENEVTYQMH-----QKIHEKPRD---SESSRKLAQRTSLDKEKP 297

  Fly   133 PPPTSHLTHLTTHSPTTIHSEHYLANGHSEHPGEGNAAVGVGGAVREPEKPFHCTVCDRRFRQLS 197
            ..|..:...:.|.....:..|..       |.|               |||:.|.||.:.||...
  Fly   298 GFPCQYCERVFTRPFEKVKHERV-------HTG---------------EKPYACEVCGKTFRVSY 340

  Fly   198 TLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNFCPKHFRQLSTLANHVKIH 262
            :||.|::.||..:||.|.||:|.|:.....::||:||:.|:.::|:.|||.||....|..|...|
  Fly   341 SLTLHLRTHTNIRPYVCTVCNKRFKSHQVYSHHLRIHSSERQFSCDACPKTFRTSVQLYAHKNTH 405

  Fly   263 TGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEGXLG----RMPLAAHHHQQQ 323
            |  ||:.|.:|.:.|.....:.||::.|           |....:| :|    .:..||....|.
  Fly   406 T--KPYRCAVCNRPFSSMYAVKNHMQTH-----------KEISSKGSVGSGTPNIKSAATSKSQA 457

  Fly   324 QHQHH----------------HQQQQHQHHPPPPSQQQQQHIDQRGVTITTLPSATTVAQHHQQH 372
            ..:.:                |.:..|      ...::|::           |:.:|.|.|
  Fly   458 AGKFYCNTCGAEYARLFALRLHMKSAH------GLVEEQEN-----------PATSTDAAH---- 501

  Fly   373 QHIQDGSPHHHFNVAALGDLSSAMQLGAVTADGSFV--TMGGV-VVGRIQHTREE 424
                         ||...|..:|:.:.|..||.:::  .:..| :||.:. |.||
  Fly   502 -------------VAETDDSETAVLIAAAEADAAYINAVVNDVDIVGTVP-TYEE 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aef1	NP_001262157.1	C2H2 Zn finger	186..206	CDD:275368	8/19 (42%)
		zf-H2C2_2	199..223	CDD:290200	12/23 (52%)
		C2H2 Zn finger	214..234	CDD:275368	7/19 (37%)
		zf-H2C2_2	227..251	CDD:290200	10/23 (43%)
		C2H2 Zn finger	242..262	CDD:275368	8/19 (42%)
		zf-H2C2_2	255..279	CDD:290200	9/23 (39%)
		C2H2 Zn finger	270..290	CDD:275368	5/19 (26%)
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	5/24 (21%)
		C2H2 Zn finger	301..321	CDD:275368	2/26 (8%)
		zf-H2C2_2	316..336	CDD:290200	9/41 (22%)
		C2H2 Zn finger	329..349	CDD:275368	8/19 (42%)
		zf-H2C2_2	341..366	CDD:290200	12/24 (50%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		C2H2 Zn finger	411..431	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	42	1.000	Inparanoid score	I2696
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050