DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aef1 and Snai1

DIOPT Version :9

Sequence 1:	NP_001262157.1	Gene:	Aef1 / 40370	FlyBaseID:	FBgn0005694	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_446257.1	Gene:	Snai1 / 116490	RGDID:	620758	Length:	264	Species:	Rattus norvegicus

Alignment Length:	236	Identity:	61/236 - (25%)
Similarity:	109/236 - (46%)	Gaps:	28/236 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 QQQHHQQQQQQSSGPPSVPPPPTELP--------LPFQMHLSGISAEAHSAAQAAAMAAAQAAAA 122
            ||.:.|.....:..||.|..|...||        :|....::..:.....:.:||.:.   :.:.
  Rat    32 QQPYDQAHLLAAIPPPEVLNPAASLPTLIWDSLLVPQVQPVAWATLPLRESPRAAELT---SLSD 93

  Fly   123 QAAAAEQQQPPPPTSHLTHLTTHSPTTIHSEHYLANGHSEHPGEGN-----AAVGVGGAVREPE- 181
            :.:....|.|.||:...:..::.|.:::.:|.::|     .||.|.     |.:.|   .::|:
  Rat    94 EDSGKSSQPPSPPSPAPSSFSSTSASSLEAEAFIA-----FPGLGQLPKQLARLSV---AKDPQS 150

  Fly   182 -KPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNFC 245
             |.|:|..|::.:..|..|..|::.||  .|..|..|.|.|.:...|..|::.||||||::|:.|
  Rat   151 RKAFNCKYCNKEYLSLGALKMHIRSHT--LPCVCTTCGKAFSRPWLLQGHVRTHTGEKPFSCSHC 213

  Fly   246 PKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNH 286
            .:.|...|.|..|::.|:..|.::|..|.:.|.:.|.|:.|
  Rat   214 NRAFADRSNLRAHLQTHSDVKRYQCQACARTFSRMSLLHKH 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aef1	NP_001262157.1	C2H2 Zn finger	186..206	CDD:275368	5/19 (26%)
		zf-H2C2_2	199..223	CDD:290200	9/23 (39%)
		C2H2 Zn finger	214..234	CDD:275368	6/19 (32%)
		zf-H2C2_2	227..251	CDD:290200	11/23 (48%)
		C2H2 Zn finger	242..262	CDD:275368	6/19 (32%)
		zf-H2C2_2	255..279	CDD:290200	7/23 (30%)
		C2H2 Zn finger	270..290	CDD:275368	6/17 (35%)
Snai1	NP_446257.1	C2H2 Zn finger	156..176	CDD:275368	5/19 (26%)
		COG5048	<177..>253	CDD:227381	27/77 (35%)
		zf-C2H2	180..202	CDD:278523	6/21 (29%)
		C2H2 Zn finger	182..202	CDD:275368	6/19 (32%)
		zf-H2C2_2	195..218	CDD:290200	10/22 (45%)
		zf-C2H2	208..230	CDD:278523	6/21 (29%)
		C2H2 Zn finger	210..230	CDD:275368	6/19 (32%)
		C2H2 Zn finger	238..255	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000