DRSC/TRiP Functional Genomics Resources

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Protein Alignment barc and Htatsf1

DIOPT Version :10

Sequence 1:NP_649313.1 Gene:barc / 40369 FlyBaseID:FBgn0037081 Length:556 Species:Drosophila melanogaster
Sequence 2:NP_082518.1 Gene:Htatsf1 / 72459 MGIID:1919709 Length:757 Species:Mus musculus


Alignment Length:420 Identity:177/420 - (42%)
Similarity:248/420 - (59%) Gaps:54/420 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   151 DEQKKWVPKHPNPGQEGVCGVDEHGERTYTDK--DGVEFFWDATKSAWFPKIDDDFMARYQMNYG 213
            |||.:....:....:||....:..||.....:  |...:.||..|.||||||.:||:|.||.|||
Mouse    13 DEQLRMQELYGGDPKEGDTQNEPSGEAHSLGQPPDDTPYEWDLDKKAWFPKITEDFIATYQANYG 77

  Fly   214 FID-------------NTSAGEK--EKAEKEAAEAKRKEEELKRMTAEAEAAMSRDNPASSAAVP 263
            |..             ||.|.|:  :|...|..::|||.|                         
Mouse    78 FSSDGASSSTANVQDANTKAVEEPPQKEVPETPDSKRKGE------------------------- 117

  Fly   264 TGKRKAQEPPKWFEMDPLQNTKVYVSNLPLDITMDEFADLMGKCGMVMRDPQTQKFKLKLYAEKD 328
              ||||:.  .||.::..:||.||||.||.|||:|||..||.|.|::||||||::||:|||.:..
Mouse   118 --KRKAES--GWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDDQ 178

  Fly   329 GQIKGDGLCDYIKVESVNLALKILDEYNLRGHKIRVQRAQFQMRGEYNPALKPKRKKKDKEKLQK 393
            |.:||||||.|:|.|||.||||:|||..:||:|:.|:.|:||::|||: |.|.|:|.||.:|...
Mouse   179 GNLKGDGLCCYLKKESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYD-ASKKKKKCKDYKKKLS 242

  Fly   394 MKEKLFDWRPDKLRG-ERSKNEKTVIIKNLFTPELFEKEVELILEYQNNLREECSKCGMVRKVVI 457
            :::|..||||::..| .|.::|:.||:||:|.|..||.:..::.|.:.:||.||||.|.:||:::
Mouse   243 LQQKQLDWRPERRAGPNRLRHERVVILKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLL 307

  Fly   458 YDRHPDGVAQINMASPEEADLVIQMMQGRYFGQRQLSAEAWDGKTKYKIEESAVEAHERLSKWDE 522
            :||||||||.::...|||||..||.:.||:||.||::|:||||.|.|::||::.|..|||..|:.
Mouse   308 FDRHPDGVASVSFREPEEADHCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRGWEA 372

  Fly   523 FLAEEETDKKASEDMKEEDVDSPENQLLPG 552
            ||...|    ||..::.  :||......||
Mouse   373 FLNAPE----ASRGLRR--MDSIAGSERPG 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
barcNP_649313.1 RRM1_TatSF1_like 283..373 CDD:409723 55/89 (62%)
RRM2_TatSF1_like 414..504 CDD:409724 46/89 (52%)
Htatsf1NP_082518.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..54 8/40 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 80..123 14/69 (20%)
RRM1_TatSF1_like 133..223 CDD:409723 55/89 (62%)
U2AF homology motif (UHM). /evidence=ECO:0000250|UniProtKB:O43719 260..354 47/93 (51%)
RRM2_TatSF1_like 264..354 CDD:409724 46/89 (52%)
Mediates interaction with the P-TEFb complex. /evidence=ECO:0000250|UniProtKB:O43719 382..757 4/17 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 383..417 4/16 (25%)
2A1904 <404..608 CDD:273344
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 432..757
Blue background indicates that the domain is not in the aligned region.

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