Protein Alignment barc and cus-2

DIOPT Version :10

• Sequence 1: NP_649313.1
• Gene: barc / 40369
• FlyBaseID: FBgn0037081
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_490765.1
• Gene: cus-2 / 171656
• WormBaseID: WBGene00022025
• Length: 442
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 165/518 - (31%)
• Similarity: 274/518 - (52%)
• Gaps: 93/518 - (17%)

  Fly    40 VPEVDDKPTENKPQSDNH-----ADKTDETPSQDFAAYEEHMTYGADGGAI-YTDPSTKQKYKWC 98
            |||.::...|::...:.|     |...|::.|:.|...:.:..||.||..: :.|
 Worm     5 VPETEENEEESQKIDEIHEIPAQAIIIDQSFSRRFLNNKWYGKYGEDGDLLEHID---------- 59

  Fly    99 ATGNNWQPLGVDEDVDGQAEDPYENEHYKWCPKSQQWLPKKQETET--EHYKWDDEQKKWVPKHP 161
               .:|:|:|:|| |:.               .||.|..::.:.:.  .||.||:|:|:||||
 Worm    60 ---EDWEPVGLDE-VEF---------------LSQLWFEQEDQEKKAHRHYDWDEEKKEWVPK-- 103

  Fly   162 NPGQEGVCGVDEHGERTYTDKDGVEFFWDATKSAWFPKIDDDFMARYQMNYGF-IDNTSAGEKEK 225
             ..||                                ::::||:|.||.|||. .|:......|:
 Worm   104 -AKQE--------------------------------EVNEDFIAEYQANYGVQYDDIYKKMDEE 135

  Fly   226 AEKEAAEAKRKEEELKRMTAEAEAAMSRDNPASSAAVPTGKRKAQEPPKWFEMDPLQNTKVYVSN 290
            .:::||:|::::||.|....:.:..:.....|...              |.::....:. |||||
 Worm   136 LQEKAAKAQKEDEEKKEKKRKKKVGLGAGEDAKEG--------------WLDLGDKVHA-VYVSN 185

  Fly   291 LPLDITMDEFADLMGKCGMVMRDPQTQKFKLKLYAEKDGQIKGDGLCDYIKVESVNLALKILDEY 355
            ||.|||.:||...|.|||::..|.:|.|.|.|||.|::|::||||.|.|||.|||.||..|||..
 Worm   186 LPEDITDEEFQKFMSKCGVIQPDIRTNKPKCKLYREENGKLKGDGRCCYIKKESVELACNILDGA 250

  Fly   356 NLRGHKIRVQRAQFQMRGEYNPALKPKRK--KKDKEKLQKMKEKLFDWRPDKLRGERSKNEKTVI 418
            ||.|.:::|:.|:|:|:|:::||.| :||  ...|::..:.:.|:|:|.|||.|..|.|::.|||
 Worm   251 NLNGREVKVEEARFEMKGDFDPARK-RRKLTAAQKKRYMEQQNKIFEWTPDKPRNYRPKSDCTVI 314

  Fly   419 IKNLFTPELFEKEVELILEYQNNLREECSKCGMVRKVVIYDRHPDGVAQINMASPEEADLVIQMM 483
            :|||||.|:..|...|:|:.:..:.:.|.|.|:|:|||:|..|||||..:...:.||:|:.::.:
 Worm   315 VKNLFTQEMMNKNAALMLDLKEEMTQSCQKYGIVKKVVVYANHPDGVVSVTFPTTEESDMAVKYL 379

  Fly   484 QGRYFGQRQLSAEAWDGKTKYKIEESAVEAHERLSKWDEFL--AEEETDKKASEDMKEEDVDS 544
            .||....|:|:||.|||:||:|:||:..:..:|..::::::  ...||.:::.:|..:|..|:
 Worm   380 HGRVVDGRKLTAELWDGRTKFKVEETEEDEEKRRKEYEKYIEGGSSETKEESDDDDDDEAEDN 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
barc	NP_649313.1	RRM1_TatSF1_like	283..373	CDD:409723	48/89 (54%)
		RRM2_TatSF1_like	414..504	CDD:409724	38/89 (43%)
cus-2	NP_490765.1	RRS1	<93..142	CDD:470484	21/83 (25%)
		RRM1_TatSF1_like	179..268	CDD:409723	48/89 (54%)
		RRM2_TatSF1_like	310..400	CDD:409724	38/89 (43%)