DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and REG4

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001152824.1	Gene:	REG4 / 83998	HGNCID:	22977	Length:	158	Species:	Homo sapiens

Alignment Length:	156	Identity:	32/156 - (20%)
Similarity:	59/156 - (37%)	Gaps:	45/156 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 CPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDA------LSG 121
            |.|.:....::||....:..:|.:|...|:...     .|.|    |...|..::|      :||
Human    30 CAPGWFYHKSNCYGYFRKLRNWSDAELECQSYG-----NGAH----LASILSLKEASTIAEYISG 85

  Fly   122 --ENDPIWLGATYDHHNNRWQW---------SMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCA 175
              .:.|||:|........:|||         |.||:::..:...      .::.||:..|
Human    86 YQRSQPIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHC------AEMSSNNNFL----- 139

  Fly   176 IYDPSLKYRWSARPCSDKLRFICQHK 201
                    .||:..|:.:..|:|:::
Human   140 --------TWSSNECNKRQHFLCKYR 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	30/142 (21%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
REG4	NP_001152824.1	CLECT_REG-1_like	30..156	CDD:153064	32/153 (21%)
		Carbohydrate-binding	98..103		0/4 (0%)
		Carbohydrate-binding	135..137		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910