DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and LOC689757

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001094489.2	Gene:	LOC689757 / 689757	RGDID:	1588731	Length:	262	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	48/216 - (22%)
Similarity:	74/216 - (34%)	Gaps:	60/216 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KMWCCQVFILALFAHTIAVEFH-------------GSAARAEINFEGPSPAHSQDTAAPTSRPKR 57
            |.:||...::.:.|..|.|...             .:...|.||  ..|.|...:|:
  Rat    83 KRYCCYGGVITVVAIAIVVPLSVTLSVKQMEQTSINNTFAASIN--NTSAASINNTS-------- 137

  Fly    58 RVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRL-FLQKQDALSG 121
               |.||..:...|..|:...:..|:|..:..||..:.|.|.    ..|.:..| ||::....||
  Rat   138 ---AACPSNWTEYGNKCFYFSEYTSNWTFSKDFCAAQGAELA----RFDTEEELNFLKRYKGSSG 195

  Fly   122 ENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPL--DNNCAIYDPSLKYR 184
                .|:|...:...:.|:|        ||     ::.|..|:    |:  |..|......|...
  Rat   196 ----YWIGLHRESSEHPWKW--------TD-----NTQYNNLV----PIRGDGQCGFLSDQLNIS 239

  Fly   185 WS----ARP--CSDKLRFICQ 199
            .|    .||  ||...::|.|
  Rat   240 SSRVYVERPWICSKPKKYISQ 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	32/135 (24%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
LOC689757	NP_001094489.2	CLECT_NK_receptors_like	140..253	CDD:153063	32/137 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345302
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930