DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and Clec5a

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001102847.1	Gene:	Clec5a / 679787	RGDID:	1584755	Length:	190	Species:	Rattus norvegicus

Alignment Length:	161	Identity:	36/161 - (22%)
Similarity:	56/161 - (34%)	Gaps:	42/161 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLT---EPGK 103
            |..|..||.|.:.           .||:  ..|:......|.|..:..:|..|.:.|.   .|
  Rat    65 PTRSSGTACPNNW-----------DFHQ--GRCFFFSTSESPWKNSRDYCATKGSTLAIVDTP-- 114

  Fly   104 HADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQ 168
               :||: ||  ||....||  .::|........:|:|.             .:|.:...::| |
  Rat   115 ---KKLK-FL--QDRAGAEN--YFIGLIRQPGEKKWRWV-------------NNSVFKGNVTN-Q 157

  Fly   169 PLDNNCAIYDPSLKYRWSARPCSDKLRFICQ 199
            ..:.||...  .|...:.|..|....|:||:
  Rat   158 EQNFNCVTI--GLTMTFDAASCDISYRWICE 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	29/129 (22%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
Clec5a	NP_001102847.1	CLECT_NK_receptors_like	73..186	CDD:153063	31/151 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930