DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and REG1B

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_006498.1	Gene:	REG1B / 5968	HGNCID:	9952	Length:	166	Species:	Homo sapiens

Alignment Length:	162	Identity:	38/162 - (23%)
Similarity:	68/162 - (41%)	Gaps:	21/162 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNA-NLTEPGKHADRK 108
            ||...:.|..|..|:  .||...:...:.||...:...:|::|..:|::.|: ||......|:..
Human    20 SQGQESQTELPNPRI--SCPEGTNAYRSYCYYFNEDPETWVDADLYCQNMNSGNLVSVLTQAEGA 82

  Fly   109 LRLFLQKQDALSGENDPIWLGATYDHHNNRWQWS----MSGRNLSTDSFSRTDSAYVQLISNSQP 169
            ....|.|:.:....|  :|:|......|.||.||    :|.::..|.|.|..::.|...::
Human    83 FVASLIKESSTDDSN--VWIGLHDPKKNRRWHWSSGSLVSYKSWDTGSPSSANAGYCASLT---- 141

  Fly   170 LDNNCAIYDPSLKYRWSARPCSDKLRFICQHK 201
               :|:.:.     :|....|..|..|:|:.|
Human   142 ---SCSGFK-----KWKDESCEKKFSFVCKFK 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	30/130 (23%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
REG1B	NP_006498.1	CLECT	36..164	CDD:413318	32/141 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910