DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and Klri1

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001012667.1	Gene:	Klri1 / 503651	RGDID:	1359344	Length:	243	Species:	Rattus norvegicus

Alignment Length:	145	Identity:	30/145 - (20%)
Similarity:	57/145 - (39%)	Gaps:	33/145 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 CPPKFH---RVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHAD-RKLRLFLQKQDALSGEN 123
            |.|..|   ..|.:.|.......||.|:...|::.|::|.:....|: ..|.||     .::|
  Rat   127 CDPCSHDWIAFGNNFYLFFRGTKSWAESKSACEELNSHLLDIDSKAELENLLLF-----EING-- 184

  Fly   124 DPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLKYRWSAR 188
               |:..    ..|:..||      |:::.::.....:     .:..:::|.....|   ::.|.
  Rat   185 ---WILV----KKNQTNWS------SSENETKLQHTLI-----DEKKNHSCRYLRGS---QFIAD 228

  Fly   189 PCSDKLRFICQ-HKM 202
            .||.|..:.|: :||
  Rat   229 DCSSKKPYACEFNKM 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	24/127 (19%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
Klri1	NP_001012667.1	ITIM motif 1. /evidence=ECO:0000250\|UniProtKB:P27812	16..21
		ITIM motif 2. /evidence=ECO:0000250\|UniProtKB:P27812	47..52
		CLECT_NK_receptors_like	130..239	CDD:153063	25/136 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345306
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930