DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and Clec7a

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001166857.1	Gene:	Clec7a / 502902	RGDID:	1565140	Length:	235	Species:	Rattus norvegicus

Alignment Length:	168	Identity:	36/168 - (21%)
Similarity:	60/168 - (35%)	Gaps:	27/168 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 EGPSPAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPG 102
            |..:|:.:..|....|.|       |.|.:......||......:||..:...|....|:|.
  Rat    92 EKVAPSKASQTTGVFSGP-------CLPNWIMHAKSCYLFSFSENSWYGSRRHCSQLGAHLL--- 146

  Fly   103 KHADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNS 167
            |..:.|...|::.|.: |...:..|:|.:.:.....|.|. .|...:.:||.         :.|:
  Rat   147 KIDNAKEFEFIESQTS-SHRVNSFWIGLSRNQSEGPWFWE-DGSAFTPNSFQ---------VRNT 200

  Fly   168 QP---LDNNCAIYDPSLKYRWSARPCSDKLRFICQHKM 202
            .|   |.:||.....|..|.   :.|......||:.::
  Rat   201 APQESLPHNCVWIHGSEVYN---QMCIASSFTICEKEL 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	29/128 (23%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
Clec7a	NP_001166857.1	Ly49	34..>61	CDD:400616
Clec7a	NP_001166857.1	CLECT_NK_receptors_like	110..233	CDD:153063	31/139 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345316
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930