DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and Clec9a

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001102824.1	Gene:	Clec9a / 502901	RGDID:	1562513	Length:	241	Species:	Rattus norvegicus

Alignment Length:	143	Identity:	37/143 - (25%)
Similarity:	56/143 - (39%)	Gaps:	24/143 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 CPPKFHRVGTDCYSLVDQRSSWLEAHFFC-KDKNANLTEPGKHADRKLRLFLQKQDALSGENDPI 126
            |||.:.:.|..||...|:..:|..:...| |:.::.|....|.....:.|.:.|   |.|..: .
  Rat   113 CPPNWIQNGKSCYYAFDRWETWNNSKKSCLKEGDSLLQIDSKEEMEFINLSIWK---LKGGYE-Y 173

  Fly   127 WLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQ---PLDNNCAIYDPSLKYRWSAR 188
            |:|...|..:..|.|......||  ....||    :.:|.||   .|.::..|.|
  Rat   174 WVGVFQDGPSGSWFWEDGSSPLS--DLLPTD----RQLSASQICGYLKDHTLISD---------- 222

  Fly   189 PCSDKLRFICQHK 201
            .||:...|||:.|
  Rat   223 NCSNWKYFICEKK 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	32/129 (25%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
Clec9a	NP_001102824.1	ITAM-like	5..10
Clec9a	NP_001102824.1	CLECT_NK_receptors_like	113..234	CDD:153063	36/140 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930