DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and Clec12b

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001102823.1	Gene:	Clec12b / 502900	RGDID:	1560487	Length:	275	Species:	Rattus norvegicus

Alignment Length:	147	Identity:	36/147 - (24%)
Similarity:	57/147 - (38%)	Gaps:	35/147 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 CPPKFHRVGTDCYSL-VDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPI 126
            ||..:...|..||.. .::..||.::...|.||||.|.:.....:|.|   ||.|  ||......
  Rat   142 CPKTWQWHGNSCYYFSANEEKSWRDSRKDCTDKNATLVKIDSIEERDL---LQSQ--LSLTFSFF 201

  Fly   127 WLGATYDHHNNRWQWS---------MSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLK 182
            |||.::|..:..|.|.         .:.:.|::.:.||                 .||.::....
  Rat   202 WLGLSWDSSSRNWLWEDGSLPPPTLFNEKELASFNGSR-----------------ECAYFERGNI 249

  Fly   183 YRWSARPCSDKLRFICQ 199
            |   ...||.::.:||:
  Rat   250 Y---VSRCSAEISWICE 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	33/136 (24%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
Clec12b	NP_001102823.1	CLECT_NK_receptors_like	142..264	CDD:153063	36/147 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345319
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930