DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and CLEC2A

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001124183.1	Gene:	CLEC2A / 387836	HGNCID:	24191	Length:	174	Species:	Homo sapiens

Alignment Length:	104	Identity:	20/104 - (19%)
Similarity:	38/104 - (36%)	Gaps:	18/104 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 CPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIW 127
            |...:..|...|:...|...:|..:..||..:.|.|.:.....|.:   ||::.    ...|..|
Human    58 CSGDWLGVRDKCFYFSDDTRNWTASKIFCSLQKAELAQIDTQEDME---FLKRY----AGTDMHW 115

  Fly   128 LGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISN 166
            :|.: ....:.|:|:.          ..|.:.:.::|.|
Human   116 IGLS-RKQGDSWKWTN----------GTTFNGWFEIIGN 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	18/93 (19%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
CLEC2A	NP_001124183.1	predicted transmembrane domain	28..50
		predicted extracellular domain	51..174		20/104 (19%)
		CLECT_NK_receptors_like	58..169	CDD:153063	20/104 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151778
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930