DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and KLRD1

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	XP_011518952.1	Gene:	KLRD1 / 3824	HGNCID:	6378	Length:	220	Species:	Homo sapiens

Alignment Length:	188	Identity:	39/188 - (20%)
Similarity:	70/188 - (37%)	Gaps:	47/188 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 CPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIW 127
            |..|:.....:||.:..::.:|.|:...|..:.::|.:        |:...:.||.:|......|
Human    61 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQ--------LQNTDELQDFMSSSQQFYW 117

  Fly   128 LGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLKYRWSARPCSD 192
            :|.:|...:..|.|. :|..||...|...::...:          ||..|:|:          .:
Human   118 IGLSYSEEHTAWLWE-NGSALSQYLFPSFETFNTK----------NCIAYNPN----------GN 161

  Fly   193 KLRFICQHKMPKVSGPNRYKIYNRWNA----TYPNE-QANEVVL------EILEPREN 239
            .|...|:.|       |||.....|.:    |...| :||..:.      ::|..|:|
Human   162 ALDESCEDK-------NRYIFLQGWRSLRKLTVMTEGKANTSLYAWQQKGDVLSKRKN 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	25/125 (20%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
KLRD1	XP_011518952.1	CLECT_NK_receptors_like	61..174	CDD:153063	30/148 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151794
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930