DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and KLRC3

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_031359.2	Gene:	KLRC3 / 3823	HGNCID:	6376	Length:	257	Species:	Homo sapiens

Alignment Length:	138	Identity:	29/138 - (21%)
Similarity:	54/138 - (39%)	Gaps:	26/138 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PAHSQDTAAPTSR-PKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNAN--LTEPGK 103
            |...|:.::|.:| .|.|....||.::......||.:..:|.:|.|:...|..||::  |....:
Human    95 PFLEQNNSSPNARTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLQACASKNSSSLLCIDNE 159

  Fly   104 HADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQ 168
            ...:.|...|...          |:|...:..::.|. :::|            .|:...|.:|.
Human   160 EEMKFLASILPSS----------WIGVFRNSSHHPWV-TING------------LAFKHEIKDSD 201

  Fly   169 PLDNNCAI 176
            ..:.|||:
Human   202 HAERNCAM 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	21/105 (20%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
KLRC3	NP_031359.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
KLRC3	NP_031359.2	CLECT_NK_receptors_like	117..227	CDD:153063	23/116 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151782
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930