DRSC/TRiP Functional Genomics Resources

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Protein Alignment rgn and Mns1

DIOPT Version :9

Sequence 1:NP_001246866.1 Gene:rgn / 40368 FlyBaseID:FBgn0261258 Length:808 Species:Drosophila melanogaster
Sequence 2:NP_001007753.1 Gene:Mns1 / 363093 RGDID:1549718 Length:498 Species:Rattus norvegicus


Alignment Length:531 Identity:134/531 - (25%)
Similarity:251/531 - (47%) Gaps:144/531 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   361 RERQRRLKEERQRLQREEQQRRQRLHHDEPKPQVNPQVKPQVIDELRQRSGEDLDKNQTDEHEQK 425
            ::|.....|:.|:|  .::..|:.||             .||:::|.:::...:.:|:.||..::
  Rat     4 KKRAMSFSEKHQQL--VDENFRKSLH-------------VQVLNKLERQAKNQVVQNENDERVER 53

  Fly   426 ------LRNEQ-----EKKLR--EEQQKQRD---EQEQKDREEQDRLKQE-------EEQARTHQ 467
                  |:|||     |:.::  ||.::.||   |||::...|..|||.|       .:|.|.:.
  Rat    54 QRFLRVLQNEQFELDMEEAVQKAEENKRMRDRQLEQEERLANELARLKHESLKDEKMRQQVRENS 118

  Fly   468 KELKENQEQQLRELKAKQEREKQ--ERD---YQQQKREHELE--LLKQRQAEADRQHAADEEAEK 525
            .||:| .||:|:.....:||..|  |:|   |:|.||:.|:|  ::::.:.....::...|:.:|
  Rat   119 IELRE-LEQKLKAAYMNKERAAQIVEKDVIKYEQMKRDAEIERIMMEEHKRLLKEENVKQEKRDK 182

  Fly   526 LRLE-RIQKQRELEAQQRRERE--EQRRKQR----------------EEQEEQDRQNHAKRLAEE 571
            .|.: .:..:::||.|:||::|  ||..|::                |.|::.:::|..::..:|
  Rat   183 ERAQYYVDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQKLEKRNAIQKYIKE 247

  Fly   572 -KRLHDLYAERIRLANTEREKQLAEAHEAKRLEELKLQEQLKKQEDERQEQIRREQEEEEKRLE- 634
             :|..||:          |:|:..|..|..|    |:.|..|.||....|::.|.||.||||:: 
  Rat   248 FQRAQDLW----------RQKKREEMEEENR----KILEFAKIQEQREGERMARVQESEEKRVQR 298

  Fly   635 ----LERLEEARRFEEKELKRLHEENQRRE-------------EQKLQRER--------EIALRE 674
                :::|||..| :..:|:|:.:|....|             ||:|:::|        ::||||
  Rat   299 QNLLIQKLEETLR-QRDDLERVRQELYLEEYAEFIKLKMKEEVEQRLRKQRDRKQDFKDQMALRE 362

  Fly   675 AAEKKLAEEEEMLRK----EVAEEERKVKQRLEDEMRQAEEARKAKEAEERAAEEAKAAEQKRRV 735
            ...:...||||..:|    :.||::|       .|:..|::.| .|:.|.:.|.|....|::.:.
  Rat   363 VLLQAAKEEEEAFKKAMLAKFAEDDR-------IELMNAQKQR-MKQLEHKRAVEKLIEERRNQF 419

  Fly   736 EAAKKKADEEVKAK----------LEEKR----REYVTRISALSP------EDQKKFI--EMRK- 777
            .|.|::..||::.:          :||:|    :|:.:::....|      ||....:  |.|| 
  Rat   420 LADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHASKLLGYLPKGVFKKEDDVDMLGEEFRKA 484

  Fly   778 --RRKQLKEKK 786
              ::.::.|:|
  Rat   485 YQKKSEVCEEK 495

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rgnNP_001246866.1 CLECT 74..200 CDD:153057
GBP_C <414..508 CDD:303769 39/123 (32%)
TPH 421..756 CDD:290579 113/428 (26%)
coiled coil 483..494 CDD:293879 5/15 (33%)
Mns1NP_001007753.1 TPH 117..462 CDD:290579 94/368 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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