DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and Klrb1a

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001010964.1	Gene:	Klrb1a / 362443	RGDID:	1586149	Length:	223	Species:	Rattus norvegicus

Alignment Length:	219	Identity:	48/219 - (21%)
Similarity:	79/219 - (36%)	Gaps:	61/219 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SH----KMWCCQ--VFILALFAHTIAVEFHGSAARAEINFEGPSPAHSQDTAAPTSRPKRRVYAL 62
            ||    |:.|..  :.:|||...:|.|.........|     |.....|:..:.|..|.:   ..
  Rat    37 SHRLALKLSCAGLILLVLALVGMSILVRVLVQKPSVE-----PCRVLIQENLSKTGSPAK---LK 93

  Fly    63 CPPKF--HRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDAL------ 119
            ||..:  ||  ..|:.:.....:|.|:...|..|.|.|            |.:|.|:.|
  Rat    94 CPKDWLSHR--DKCFHVSQTSITWKESLADCGGKGATL------------LLVQDQEELRFLRNL 144

  Fly   120 -SGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRT-----DSAYVQLISNSQPLDNNCAIYD 178
             ...:...|:|.:|...:..|:| ::|..|::|..|.|     ||.  ..:|..:.|..:|.
  Rat   145 TKRISSSFWIGLSYTLSDENWKW-INGSTLNSDVLSITGDTEKDSC--ASVSQDKVLSESCD--- 203

  Fly   179 PSLKYRWSARPCSDKLRFICQHKM 202
                        ||.: ::||.::
  Rat   204 ------------SDNI-WVCQKEL 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	29/137 (21%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
Klrb1a	NP_001010964.1	LCK-binding motif	32..35
		PHA03097	42..210	CDD:222982	44/208 (21%)
		CLECT_NK_receptors_like	94..212	CDD:153063	33/150 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345314
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930