DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and CLEC2D

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001004419.1	Gene:	CLEC2D / 29121	HGNCID:	14351	Length:	194	Species:	Homo sapiens

Alignment Length:	193	Identity:	41/193 - (21%)
Similarity:	72/193 - (37%)	Gaps:	45/193 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 MWCCQVFILALFAHTIAVEFHG--SAARAEINFEGPSPAHSQDTAAPTSRPKRRVYALCPPKFHR 69
            :|  ::|.|.:|...|......  ||.||..:.|                |...:.|.||..:..
Human    35 IW--RLFFLIMFLTIIVCGMVAALSAIRANCHQE----------------PSVCLQAACPESWIG 81

  Fly    70 VGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIWLGATYDH 134
            ....|:...|...:|..:..||..::|:|.:  ..:.::|...|:    ..|.:|. |:|.:.:
Human    82 FQRKCFYFSDDTKNWTSSQRFCDSQDADLAQ--VESFQELNFLLR----YKGPSDH-WIGLSRE- 138

  Fly   135 HNNRWQWSMSGRNLSTDSFSRTDSA--YVQLIS-----NSQPLDNNCAIYDPSLKYRWSARPC 190
            ....|:| ::|...:.....:.|.|  ||..:|     |.:|:         .:.|..|.|.|
Human   139 QGQPWKW-INGTEWTRQLVMKEDGANLYVAKVSQVPRMNPRPV---------MVSYPGSRRVC 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	27/124 (22%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
CLEC2D	NP_001004419.1	CLECT_NK_receptors_like	75..171	CDD:153063	22/104 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930