DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and Klrh1

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001014997.1	Gene:	Klrh1 / 232415	MGIID:	2685002	Length:	223	Species:	Mus musculus

Alignment Length:	212	Identity:	44/212 - (20%)
Similarity:	71/212 - (33%)	Gaps:	48/212 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WCCQVFILA------LFAHTI-AVEFHGSAARAEINFE---------GPSPAHSQD---TAAPTS 53
            |...|.||.      |.:.|: ...|..:.:..:|.:|         .....||..   |||
Mouse    32 WRISVVILGTVCLCLLISSTVFGYWFFQATSNFKIQYEKDKNESAVSSMEVVHSSGLLLTAA--- 93

  Fly    54 RPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDA 118
               |:....|...:...|..||...::..:|.|:...||...:.|   .|...|:.:.|:|.|
Mouse    94 ---RKGCYTCQGGWSCCGGKCYFFSEEEKTWDESEASCKVLGSLL---AKIDSREEQNFIQSQ-- 150

  Fly   119 LSGENDPIWLGATYDHHNNRWQW-SMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLK 182
               .|...|:|  .....:::|| ......||:|         :...:.:...|..|....|.
Mouse   151 ---VNYSYWVG--LHKKGSQFQWVHHKDAKLSSD---------LDFHTATHVADAECGYIKPK-- 199

  Fly   183 YRWSARPCSDKLRFICQ 199
             ..:..||.....:||:
Mouse   200 -NLNVAPCHRYFYYICK 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	27/127 (21%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
Klrh1	NP_001014997.1	Ly49	31..114	CDD:285577	19/87 (22%)
Klrh1	NP_001014997.1	CLECT_NK_receptors_like	100..216	CDD:153063	29/138 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841898
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930