DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and clec-146

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001254401.1	Gene:	clec-146 / 175004	WormBaseID:	WBGene00013008	Length:	189	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	44/203 - (21%)
Similarity:	72/203 - (35%)	Gaps:	40/203 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VFILALFAHTIAVEFHGSAARAEI-----------NFEGPSPAHSQDTAAPTSRPKRRVYALCPP 65
            :|.:.|.|..:..:|:....|:..           ||||.:....:......:|.::.:..|...
Worm     4 IFSVLLLAAVVQTQFNFHGMRSFFSTDEEFPTQLQNFEGRTETEIRTLKEKVARLEKLIDGLQSV 68

  Fly    66 KFHRVGT----DCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPI 126
            ......|    ..|.|.::|.||..|...|:...|:|......|...   |:......|..:|..
Worm    69 LMKEWNTTESGSKYRLFEERKSWDNAERHCQGFGAHLAIIDNEAKNG---FVTNLINSSETSDFA 130

  Fly   127 WLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLKYRWSARPCS 191
            |:|                  :.|.:.::|.:.:....|.| |:| .||:.|  .|..||.|.|.
Worm   131 WIG------------------MKTKTTTQTSTPFTNFDSES-PID-GCAVMD--AKGVWSIRSCI 173

  Fly   192 DKLRFICQ 199
            ....|:||
Worm   174 QLRPFVCQ 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	32/126 (25%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
clec-146	NP_001254401.1	CLECT	78..181	CDD:214480	30/127 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161753
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930