DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and REG3G

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001008388.1	Gene:	REG3G / 130120	HGNCID:	29595	Length:	175	Species:	Homo sapiens

Alignment Length:	189	Identity:	42/189 - (22%)
Similarity:	62/189 - (32%)	Gaps:	63/189 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EINFEGPSPAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANL 98
            |...|.|||..|                 ||......|:.||:|.....||::|...|:
Human    28 ETQKELPSPRIS-----------------CPKGSKAYGSPCYALFLSPKSWMDADLACQ------ 69

  Fly    99 TEPGKHADRKLRLFLQKQD---------ALSGENDPIWLGATYDHHN---------NRWQWSMSG 145
                |....||...|...:         ::|.....||:|.    |:         :.|:||
Human    70 ----KRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGL----HDPTQGSEPDGDGWEWS--- 123

  Fly   146 RNLSTDSFSRTDSAYVQLISNSQPLDN--NCAIYDPSLKY-RWSARPCSDKLRFICQHK 201
               |||..:     |.....|...:.|  :|.....|..: :|....|..||.::|:.|
Human   124 ---STDVMN-----YFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFK 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	32/146 (22%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
REG3G	NP_001008388.1	CLECT_REG-1_like	40..173	CDD:153064	35/157 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000