DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rgn and KLRF2

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001177694.1	Gene:	KLRF2 / 100431172	HGNCID:	37646	Length:	207	Species:	Homo sapiens

Alignment Length:	147	Identity:	32/147 - (21%)
Similarity:	49/147 - (33%)	Gaps:	38/147 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPI 126
            |||..:......||.......:|.|:...|....|:|            |.:|..|.|....:.:
Human    77 LCPNDWLLNEGKCYWFSTSFKTWKESQRDCTQLQAHL------------LVIQNLDELEFIQNSL 129

  Fly   127 ------WLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYV--QLISNSQPLDN-NCAIYDPSLK 182
                  |:|.......|.|.|              .|..::  :|.|...|.|: :||:...:..
Human   130 KPGHFGWIGLYVTFQGNLWMW--------------IDEHFLVPELFSVIGPTDDRSCAVITGNWV 180

  Fly   183 YRWSARPCSDKLRFICQ 199
            |   :..||...:.|||
Human   181 Y---SEDCSSTFKGICQ 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	29/135 (21%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
KLRF2	NP_001177694.1	CLECT_NK_receptors_like	78..195	CDD:153063	31/146 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151791
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930