DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rgn and si:ch211-225k7.4

DIOPT Version :9

Sequence 1:	NP_001246866.1	Gene:	rgn / 40368	FlyBaseID:	FBgn0261258	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001116876.1	Gene:	si:ch211-225k7.4 / 100002702	ZFINID:	ZDB-GENE-060503-28	Length:	367	Species:	Danio rerio

Alignment Length:	179	Identity:	41/179 - (22%)
Similarity:	73/179 - (40%)	Gaps:	57/179 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CYS------LVDQRSSWLEAHFFCKDKNANLTE-PGKHADRKLRLFLQKQDALSGENDPIWLGAT 131
            |::      .|.|..:|.:|..:|:..:.:|.. ..::.:::|..|:..:.: ||..  :|:|..
Zfish   129 CFNTSRGLVFVKQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLEKFINDRKS-SGST--VWIGLF 190

  Fly   132 YDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDN-----NCAIYDPSLKYRWSARPC- 190
            .|    .||||    :.|:.||...|        |:|| ||     ||.:...:::.:|....|
Zfish   191 RD----SWQWS----DQSSSSFRYWD--------NNQP-DNRGGIENCTVITQNVQRQWHDISCE 238

  Fly   191 ---------------------SDKLRFICQHKMPKVSGPN---RYKIYN 215
                                 |:.||:..||.:..||..:   :||:.|
Zfish   239 HHFCFVLCPDKLLVVQQNLLWSEALRYCRQHHVDLVSVQSEEMQYKVMN 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rgn	NP_001246866.1	CLECT	74..200	CDD:153057	34/159 (21%)
		GBP_C	<414..508	CDD:303769
		TPH	421..756	CDD:290579
		coiled coil	483..494	CDD:293879
si:ch211-225k7.4	NP_001116876.1	CLECT	23..131	CDD:295302	1/1 (100%)
		CLECT	134..244	CDD:295302	30/129 (23%)
		CLECT	251..364	CDD:153057	10/37 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000