DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sa and TAF3

DIOPT Version :9

Sequence 1:	NP_649311.1	Gene:	sa / 40367	FlyBaseID:	FBgn0002842	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_114129.1	Gene:	TAF3 / 83860	HGNCID:	17303	Length:	929	Species:	Homo sapiens

Alignment Length:	307	Identity:	67/307 - (21%)
Similarity:	109/307 - (35%)	Gaps:	84/307 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CEVVDDVLRQSMLELLRGKFREIARQTTNWSNHAGRCAPSYFDLERTFIRMNIKVGELKAMYEGQ 85
            |.::.|||::.:.:|.||..|        :|...||..|...|:...|..|.:.:.||:
Human    31 CHLLTDVLQRYLQQLGRGCHR--------YSELYGRTDPILDDVGEAFQLMGVSLHELE------ 81

  Fly    86 PDSLVLVECNAPETQDQDFHSVPQPVLSSTKAVELAS---------TTYIPDHLPPFPGAHTYKS 141
             |.:..:|   |.|..   |.:|...:|....::...         ..||||:|||...:...:.
Human    82 -DYIHNIE---PVTFP---HQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYLPPIVSSQEEEE 139

  Fly   142 STIEKV-TD--RSYVAMR-NRHAENELNTQNALN-QYYLRCNP---------------------- 179
            .  |:| ||  .|..||: ....::||..:..:| :.:|...|
Human   140 E--EQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKG 202

  Fly   180 ---NISLFE--------ETQRD----GSGHV---LDLGPPKK-----LPYSDALMPRNQVFDTDI 221
               ::.|.|        .||:.    ...||   .||.||..     .|.:.:.||..:..:|..
Human   203 DTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKPLETKS 267

  Fly   222 YAPIEVITHKALDCRYLEKPKLHSSRPSSGN-FEEEDVEMEEPCSPG 267
            :.| :..|..:...:..:.||...|....|: ........:|..|||
Human   268 FTP-KTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPG 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sa	NP_649311.1	Bromo_TP	6..77	CDD:284856	15/55 (27%)
sa	NP_649311.1	TAF8	125..177	CDD:176263	18/56 (32%)
TAF3	NP_114129.1	BTP	5..79	CDD:128846	15/55 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	131..152		5/22 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..197		2/20 (10%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..358		22/94 (23%)
		PTZ00449	<229..388	CDD:185628	20/86 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..578
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	603..658
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	692..748
		PRK12323	<777..>847	CDD:237057
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	778..807
		PHD_TAF3	867..912	CDD:276997
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810