DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sa and ZK1320.7

DIOPT Version :9

Sequence 1:	NP_649311.1	Gene:	sa / 40367	FlyBaseID:	FBgn0002842	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_496087.2	Gene:	ZK1320.7 / 259457	WormBaseID:	WBGene00014256	Length:	371	Species:	Caenorhabditis elegans

Alignment Length:	234	Identity:	46/234 - (19%)
Similarity:	77/234 - (32%)	Gaps:	61/234 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 TTNWS---NHAGRCAPSYFDLERTFIR-MNIKVGELKAMYEGQPDSLVLVECNAPETQDQDFHSV 107
            |||:.   ...|...|....:|  |:| .|:...|...|.:.:.|   :...:.....|..|.|.
Worm     3 TTNYQLPPQKLGNLNPEQVPVE--FVRAKNVGDAEKTEMSQKRDD---VQRASNSSINDSGFGSE 62

  Fly   108 PQPVLSSTKAVELASTTYIPDHLPPFPGAHTYKSSTIEKVTDRSYVAMRNRHAENELNTQNALNQ 172
            .:.|:...|..|...   |....|       .:.:.|..:.|..:..::|..:.:..|
Worm    63 YRKVIEKAKIREKKK---IKTENP-------QEDAEIIILDDDDFAIVKNEPSTSHSN------- 110

  Fly   173 YYLRCNPNISLFEETQRDGSGHVLDLGPPKKLPYSDALMPRNQVFDTDIYAPIEVITHKALDCRY 237
            :.:|   :::.|.:..:||:...:.....||:|          :..||.|.      ..|..|
Worm   111 FNVR---DVNGFLKAAKDGNLEEIKRYLEKKIP----------IDVTDFYG------WTATMC-- 154

  Fly   238 LEKPKLHSSRPSSGNFEEEDVEMEEPCSPG-----GLGI 271
                     ....||||...:.:|....||     .|||
Worm   155 ---------AAGEGNFEVCKLLLEHGADPGVRDSHSLGI 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sa	NP_649311.1	Bromo_TP	6..77	CDD:284856	9/33 (27%)
sa	NP_649311.1	TAF8	125..177	CDD:176263	6/51 (12%)
ZK1320.7	NP_496087.2	ANK	<109..200	CDD:238125	23/113 (20%)
		ANK repeat	117..145	CDD:293786	6/37 (16%)
		Ank_2	119..206	CDD:289560	21/93 (23%)
		ANK repeat	147..178	CDD:293786	10/47 (21%)
		G-patch	263..307	CDD:279867
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900