Protein Alignment ebd2 and Jrkl

DIOPT Version :10

• Sequence 1: NP_649307.1
• Gene: ebd2 / 40363
• FlyBaseID: FBgn0037076
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_001028353.1
• Gene: Jrkl / 77532
• MGIID: 1924782
• Length: 523
• Species: Mus musculus
• Alignment Length: 347
• Identity: 70/347 - (20%)
• Similarity: 133/347 - (38%)
• Gaps: 49/347 - (14%)

  Fly    25 SRRNERNILTFYEKIAVIRYYDETNISRNSLAKMFHCCATQIRRILDKKKDLLQQLATLSEADAS 89
            |.:.:|.:||..:|:.:|:..::...|: .||.::....|.:|.|...|:.::...:  |....|
Mouse     2 SGKRKRVVLTIKDKLDIIKKLEDGGSSK-QLAVIYGIGETTVRDIRKNKEKIITYAS--SSDSTS 63

  Fly    90 IIIEEMTRKRRKFEMSAISFLLHEWVERCIQMQLNISIRNQKLKETAIRMAAVLNLP-SFRPSYR 153
            ::.:..:.|...:|  .:...:.||..:  |......|......:.|......|.:. .|.||..
Mouse    64 LLAKRKSMKPSMYE--ELDKAMLEWFNQ--QRAKGNPISGPICAKRAEFFFYALGMDGDFNPSAG 124

  Fly   154 WLSRFRNKYKYEADELGYQGENPLNQDLPVEDIIVEFKHALPNFMQRELDNPGEAISKAAVMADF 218
            ||:||  |.::...|:..:.|.....:..|||....|:    :|:::|...|.:..:.......:
Mouse   125 WLTRF--KQRHSIREINIRNERLNGDETAVEDFCNNFR----DFIEQENLQPEQIYNADETGLFW 183

  Fly   219 VNLSSENSIMS------DHPEGDNEVELVTCEPTMMSSPSSTPDAAEGEIPLQAHGDQENP---- 273
            ..|.|..:::.      .|..|:..:.::.|          |......::.|...|....|
Mouse   184 KCLPSRTTVIKGKCTVPGHNLGEERITVMCC----------TNATGLHKLKLCVVGKARKPRSFK 238

  Fly   274 -DDQINAGTSTL-LNGVFPHLAIIHQFALMNSDVQALELISQLGVHMQQQAV-----SGAYHNLS 331
             .|.:|...|.. ..|.:..|:|..|:.......|..|.:...|  :|::||     |..:.|.:
Mouse   239 STDTLNLPVSYFSQKGAWMDLSIFRQWFDKIFVPQVREYLRSKG--LQEKAVLLLDNSPTHPNEN 301

  Fly   332 LATTDGDGQDDPGEIALSELPP 353
            :.      :.|.|:|....|||
Mouse   302 VL------RSDDGQIFAKYLPP 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ebd2	NP_649307.1	CENP-B_N	27..80	CDD:461229	12/52 (23%)
		CENPB	101..166	CDD:197828	15/65 (23%)
Jrkl	NP_001028353.1	CENP-B_N	4..53	CDD:461229	12/49 (24%)
		CENPB	73..139	CDD:197828	16/71 (23%)
		DDE_1	206..385	CDD:367380	26/130 (20%)