DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ebd2 and Tigd3

DIOPT Version :9

Sequence 1:	NP_001246865.1	Gene:	ebd2 / 40363	FlyBaseID:	FBgn0037076	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001348974.1	Gene:	Tigd3 / 332359	MGIID:	2681860	Length:	470	Species:	Mus musculus

Alignment Length:	453	Identity:	91/453 - (20%)
Similarity:	150/453 - (33%)	Gaps:	165/453 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NTKGIKSRRNERNILTFYEKIAVIRYYDETNISRNSLAKMFHCCATQIRRILDKKKDLLQQLATL 83
            |||      .:.:.|:..|||.|:...||:.:|::.:|:.|.....||.||...|:.||
Mouse     4 NTK------KKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLL------ 56

  Fly    84 SEAD-ASIIIEEMTRKRRKFEMSAISFLLHEW--VERCIQMQLNISIRNQKLKETAIRMAAVLNL 145
              || .|.......:::|:.:.|.|...|..|  :.|.....:...:...|.||.|..|.
Mouse    57 --ADWCSGTANHERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMG----- 114

  Fly   146 PSFRPSYRWLSRFRNK--------------YKYEADE--LGYQGENPLN-QDLPVEDI-----IV 188
            ..|.||..||.|::.:              :..||..  |..|.:.||: :|...||:     :.
Mouse   115 QDFVPSIGWLVRWKRRNNVGFGTRQVLVPLFPPEAPPAVLPSQAQPPLSLKDFSPEDVFGCAEVP 179

  Fly   189 EFKHALP------NFMQRELDNPGEAISKAAVMAD--------FVNLSSENSIMSDHPE------ 233
            ....|:|      :.:|..|........|..|...        |..:|||....|.||:
Mouse   180 LLYRAVPGRVFECDRLQVLLCANSRGTEKRRVFVGGLQAAPRCFFGVSSEALPTSYHPDLAIPWS 244

  Fly   234 ---------------------------------GDNEVELVTCEPTMMSSPSSTPDAAEGEIPL- 264
                                             |.:.|.|:.     :|:.|:|| :..|.:.|
Mouse   245 EWLAQFDQDMGQQGRQVALLLASGVVEEWASLPGLHHVRLLP-----LSASSTTP-SLPGSVILA 303

  Fly   265 -QAHGDQENPDDQINAGTSTLLNGVFPHLAIIHQFALMNSD---------------VQALELISQ 313
             :||                     :.| .::.:.|.|.|.               :.||.:::.
Mouse   304 FKAH---------------------YRH-RLLSKLAAMQSGKEGTSLAEARASITVLDALHMVAA 346

  Fly   314 LGVHMQQQAVSGAYHNLSLATTDGDGQDDPGEIAL--------SELPPG------SIYADIDD 362
            ....:.:|.:..::....||         ||:..|        |.:|.|      |.:.|::|
Mouse   347 AWAKVPRQLILSSFVQEGLA---------PGKTPLSLDKDTEMSPVPSGLSQEEFSHFVDLED 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ebd2	NP_001246865.1	CENP-B_N	27..80	CDD:282122	17/52 (33%)
ebd2	NP_001246865.1	CENPB	101..166	CDD:197828	16/80 (20%)
Tigd3	NP_001348974.1	HTH	6..57	CDD:328727	18/64 (28%)
		HTH_Tnp_Tc5	76..133	CDD:308705	16/61 (26%)
		rve	193..360	CDD:328789	29/194 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	402..426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910