DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ebd2 and tigd3

DIOPT Version :9

Sequence 1:	NP_001246865.1	Gene:	ebd2 / 40363	FlyBaseID:	FBgn0037076	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001128294.1	Gene:	tigd3 / 100135169	XenbaseID:	XB-GENE-6457180	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	168	Identity:	41/168 - (24%)
Similarity:	76/168 - (45%)	Gaps:	20/168 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KSRRNERNILTFYEKIAVIRYYDETNISRNSLAKMFHCCATQIRRILDKKKDLLQQLATLSEADA 88
            |.||:.    |..||:.::....:...|::|:|:......:.|.|::..:::::::...
Frog    18 KKRRDS----TLAEKVKILELLQQPKASQSSVARNLGLSQSTISRVMKNREEIMERWNQ------ 72

  Fly    89 SIIIEEMTRKR-RKFEMSAISFLLHEWVERCIQMQLNISIRNQKLKETAIRMAAVLNLPSFRPSY 152
               .|...||| |.|:.:.:...|.||:......:|.||  ...|...|..:|..:..|.|:||.
Frog    73 ---NENPARKRNRPFKHAKVDEALLEWLLFAKANKLPIS--GPILMRRAEAIAKEIGCPQFKPSN 132

  Fly   153 RWLSRFRNKYK--YEADELGYQGENPL--NQDLPVEDI 186
            .||.|::.:|:  |..:.|..|....:  .||:|..:|
Frog   133 GWLWRWKERYRLFYRTEVLPCQRSGMILQGQDVPESEI 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ebd2	NP_001246865.1	CENP-B_N	27..80	CDD:282122	9/52 (17%)
ebd2	NP_001246865.1	CENPB	101..166	CDD:197828	19/66 (29%)
tigd3	NP_001128294.1	HTH	18..68	CDD:304362	11/53 (21%)
		CENPB	83..147	CDD:197828	18/65 (28%)
		rve	248..421	CDD:304425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910