DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tsr1 and AT1G42440

DIOPT Version :9

Sequence 1:	NP_649304.1	Gene:	Tsr1 / 40360	FlyBaseID:	FBgn0037073	Length:	814	Species:	Drosophila melanogaster
Sequence 2:	NP_564480.1	Gene:	AT1G42440 / 840848	AraportID:	AT1G42440	Length:	793	Species:	Arabidopsis thaliana

Alignment Length:	813	Identity:	292/813 - (35%)
Similarity:	460/813 - (56%)	Gaps:	78/813 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QANKAHKTGRHRSKGAID----NAQ-KGKIGLRPISHKHKQQQRKEQRRNQMNQLRKNKREEVLE 73
            |.|||||| |..||.:.:    |.| .|:|| :..|:..|..:....:|.:|  ||:.||..||:
plant     7 QVNKAHKT-RFSSKSSRNLHRTNLQDSGRIG-KSDSNYVKGAKAARVQRGKM--LREQKRAAVLK 67

  Fly    74 QKRKLGGQNTAPFLVCLLPMHEQIDPMSAL--EILKSCDSELVVENSPSGIV--YINLPRFKQRF 134
            :||..||.|:||.::.|.|:...:: :::|  ::||      ::.:..|||.  .:....:|.|.
plant    68 EKRASGGINSAPRVIVLFPLSASVE-LNSLGEDVLK------LLSSDGSGIASSTVASSEYKLRA 125

  Fly   135 AFVTPPVGRGNELIALDYLKVCDTTLLLTTAAFGDDE----IFDRWGQRIFNMMSAQGIPTPVVA 195
            ..:..|  .|:.|..::..||.|....:.:|:...:|    ..|.:|.:..::..:.|:|:..|.
plant   126 TVLKAP--HGDLLTCMEMAKVADLMAFVASASAPWEENSSNFIDSFGSQCLSVFRSIGLPSTTVL 188

  Fly   196 LMDLESINPKRRPAAKQAAQKVISKLLPEEKIMQLDTASEALNVMRRIGGQKKRILHNVANRPHL 260
            :.||.|...|:....|..|.::.|:...:.|....||..|....|.....|:..:.|..:.|.:
plant   189 IRDLPSDVKKKNEMKKMCASQLASEFPEDCKFYPADTRDELHKFMWLFKAQRLTVPHWRSQRSY- 252

  Fly   261 FGDVVEFKPG---SDPSDDLGTLEVTGFLRGQSLNVNGLVHIPGLGDFQLSQVVAPPDPYKLDKS 322
               :|..|.|   .|.|....||.::|:||.:.|:||.|||:.|:||||.|::....||:.|::.
plant   253 ---IVARKAGMLVDDESSGKCTLLLSGYLRARKLSVNQLVHVSGVGDFQFSKIEVLKDPFPLNER 314

  Fly   323 RDGENSEVRLLDRS-----------DPSKRTSLQSENIPDPMDAEQTWPTEDEIAASQAETKKMK 376
            ::..:.|   ||.|           ||.|:..|..||.|||:..|||||||:|:|.:....|:.:
plant   315 KNQNSME---LDDSHDEEVLKSLVPDPMKQEPLVIENTPDPLAGEQTWPTEEEMAEADKNQKQGR 376

  Fly   377 LVKR-VPKGYSEYQAAWIPDVEEVEDPDGKDDDDMSEDDDDDKEDDNEDFMSCDNKSFEDEYEK- 439
            |.|: :|:|.||||||||.|..:.||.|..|.||.....|.. ||.|::.|.  ::.|||:.:.
plant   377 LKKKTLPRGTSEYQAAWIVDETDEEDSDNGDSDDNGMVLDRG-EDSNQEGMY--DQEFEDDGKSL 438

  Fly   440 --RDSDTEEFQDTVSVASEAAINDEKYDQQMDFQEERETLKKLQQA-RTDQLWPDEIDTPLDVPA 501
              ||.|||       ..:|:.:.|   |:.:..::.::.:||:::| ..|:.:|||::||:||||
plant   439 NLRDIDTE-------TQNESEMVD---DEDLTEEQIKDEIKKIKEAYADDEEFPDEVETPIDVPA 493

  Fly   502 RERFQKYRGLESFRTSPWDAKENLPADYARIYQFQNFDRTKRRILNEAKEFE-----GVLP-GLY 560
            |.||.|||||:|||||.||..|:||.|||||:.|.|..||::.:|.:|.:.|     ..:| |.|
plant   494 RRRFAKYRGLKSFRTSSWDPNESLPQDYARIFAFDNVARTQKLVLKQALKMEEEDRDDCVPIGSY 558

  Fly   561 VTLYVINVPESRWNAFKSAQLMDN---IIVYGMLPHEHQMCVMNVVLQRMPDSEVPLKSKEQLII 622
            |.|::..||...  |.|.:.|::.   ||.:|:|.||.:|.|::..:::....|.|:|:||:|:.
plant   559 VRLHIKEVPLGA--ASKLSSLVNTTKPIIGFGLLQHESKMSVLHFSVKKYDGYEAPIKTKEELMF 621

  Fly   623 QCGYRRFVVNPIY-SQHTNGDKHKFERYFRPYETVCATFYAPIQFPPAPVLAFKVNPDS-TLALV 685
            ..|:|:|:..|:: :.:.:.||||.||:..|.....|:.|.||.|||.|::..|::..| ..|:.
plant   622 HVGFRQFIARPVFATDNFSSDKHKMERFLHPGCFSLASIYGPISFPPLPLVVLKISEGSDPPAIA 686

  Fly   686 ARGRLLSCNPDRIVLKRVVLSGHPMRINRKSASIRYMFFYKEDVEYFKPVKLRTKCGRLGHIKES 750
            |.|.|.|..|::|:||:::|:|:|.|:::..||:||||...|||::||||::.:||||.|.:||.
plant   687 ALGSLKSVEPNKIILKKIILTGYPQRVSKMKASVRYMFHNPEDVKWFKPVEVWSKCGRRGRVKEP 751

  Fly   751 LGTHGHMKCYFDGQLRSYDTAFMYLYKRVFPKW 783
            :||||.|||.|:|.::.:|...|.||||.:|||
plant   752 VGTHGAMKCIFNGVVQQHDVVCMNLYKRAYPKW 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsr1	NP_649304.1	COG5177	17..781	CDD:227504	287/806 (36%)
Tsr1	NP_649304.1	RIBIOP_C	493..781	CDD:368206	129/298 (43%)
AT1G42440	NP_564480.1	COG5177	3..782	CDD:227504	289/809 (36%)
		AARP2CN	228..308	CDD:285368	27/83 (33%)
		RIBIOP_C	487..779	CDD:282764	127/293 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	257	1.000	Domainoid score	I493
eggNOG	1	0.900	-	-		E1_COG5177
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5576
Inparanoid	1	1.050	449	1.000	Inparanoid score	I387
OMA	1	1.010	-	-		QHG54181
OrthoDB	1	1.010	-	-		D186926at2759
OrthoFinder	1	1.000	-	-		FOG0005046
OrthoInspector	1	1.000	-	-		oto3782
orthoMCL	1	0.900	-	-		OOG6_102221
Panther	1	1.100	-	-	LDO	PTHR12858
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3570
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840