DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab26 and SEC4

DIOPT Version :9

Sequence 1:	NP_001097658.1	Gene:	Rab26 / 40359	FlyBaseID:	FBgn0086913	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_116650.1	Gene:	SEC4 / 850543	SGDID:	S000001889	Length:	215	Species:	Saccharomyces cerevisiae

Alignment Length:	214	Identity:	83/214 - (38%)
Similarity:	141/214 - (65%)	Gaps:	12/214 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 IRMISSSKAPEEEDEFDIMGKVIMLGDSGVGKTSLLIRFRDGRYVPSYFLSTVGIDFRNKVVVVD 258
            :|.:|:|..  ....:|.:.|::::|||||||:.||:||.:.::.|| |::|:||||:.|.|.::
Yeast     4 LRTVSASSG--NGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPS-FITTIGIDFKIKTVDIN 65

  Fly   259 GTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQEDVVIVL 323
            |.:||||:||||||||||::|.||||.|..::|:||||::.|:.||:.|...:.|:|.::..::|
Yeast    66 GKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLL 130

  Fly   324 IGNKADCSGSERQVKREDGERLGREHNVPFMETSAKTGLNVELSFTAVARQLKSR-------GYE 381
            :|||:|.  ..|.|..:.||.|.:|..:||:|:|||...||...|..:|:.::.:       |..
Yeast   131 VGNKSDM--ETRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVG 193

  Fly   382 HGDDGKFNVHDFVRDNTKA 400
            :|.:|..:::....:::|:
Yeast   194 NGKEGNISINSGSGNSSKS 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab26	NP_001097658.1	Rab26	214..407	CDD:206695	79/194 (41%)
Rab26	NP_001097658.1	RAB	214..378	CDD:197555	75/163 (46%)
SEC4	NP_116650.1	Rab8_Rab10_Rab13_like	18..183	CDD:206659	76/167 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910