Protein Alignment Rab26 and RAB6A

DIOPT Version :10

• Sequence 1: NP_001097658.1
• Gene: Rab26 / 40359
• FlyBaseID: FBgn0086913
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_002860.2
• Gene: RAB6A / 5870
• HGNCID: 9786
• Length: 208
• Species: Homo sapiens
• Alignment Length: 172
• Identity: 75/172 - (43%)
• Similarity: 111/172 - (64%)
• Gaps: 4/172 - (2%)

  Fly   214 KVIMLGDSGVGKTSLLIRFRDGRYVPSYFLSTVGIDFRNKVVVVDGTRVKLQIWDTAGQERFRSV 278
            |::.||:..||||||:.||....:..:| .:|:||||.:|.:.::...::||:|||||||||||:
Human    15 KLVFLGEQSVGKTSLITRFMYDSFDNTY-QATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSL 78

  Fly   279 THAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQEDVVIVLIGNKADCSGSERQVKREDGE 343
            ..:|.||:.|.:::||:||..::.....|:.::|.....||:|:|:|||.|.: .:|||..|:||
Human    79 IPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLA-DKRQVSIEEGE 142

  Fly   344 RLGREHNVPFMETSAKTGLNVELSFTAVARQLKSRGYEHGDD 385
            |..:|.||.|:|||||.|.||:..|..||..|.  |.|...|
Human   143 RKAKELNVMFIETSAKAGYNVKQLFRRVAAALP--GMESTQD 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab26	NP_001097658.1	Rab26	214..407	CDD:206695	75/172 (44%)
RAB6A	NP_002860.2	Rab6	14..174	CDD:206654	71/160 (44%)
		Switch 1. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	32..50		6/18 (33%)
		Switch 2. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	69..88		12/18 (67%)