Protein Alignment Rab26 and RAB3B

DIOPT Version :10

• Sequence 1: NP_001097658.1
• Gene: Rab26 / 40359
• FlyBaseID: FBgn0086913
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_002858.2
• Gene: RAB3B / 5865
• HGNCID: 9778
• Length: 219
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 72/163 - (44%)
• Similarity: 108/163 - (66%)
• Gaps: 2/163 - (1%)

  Fly   206 EDEFDIMGKVIMLGDSGVGKTSLLIRFRDGRYVPSYFLSTVGIDFRNKVVVVDGTRVKLQIWDTA 270
            :..||.|.|::::|:|.|||||.|.|:.|..:.|: |:|||||||:.|.|.....||||||||||
Human    16 DQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPA-FVSTVGIDFKVKTVYRHEKRVKLQIWDTA 79

  Fly   271 GQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQEDVVIVLIGNKADCSGSER 335
            ||||:|::|.||||.|...:|:||:||:.:::.::.|..:|:.|:.::..::|:|||.|.. .||
Human    80 GQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDME-EER 143

  Fly   336 QVKREDGERLGREHNVPFMETSAKTGLNVELSF 368
            .|..|.|:.|..:....|.|.|||..::|..:|
Human   144 VVPTEKGQLLAEQLGFDFFEASAKENISVRQAF 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab26	NP_001097658.1	Rab26	214..407	CDD:206695	69/155 (45%)
RAB3B	NP_002858.2	Rab3	22..186	CDD:206657	70/157 (45%)
		Switch 1. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	45..58		6/13 (46%)
		Switch 2. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	78..96		12/17 (71%)