Protein Alignment Pc and CBX8

DIOPT Version :9

• Sequence 1: NP_524199.1
• Gene: Pc / 40358
• FlyBaseID: FBgn0003042
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_065700.1
• Gene: CBX8 / 57332
• HGNCID: 15962
• Length: 389
• Species: Homo sapiens
• Alignment Length: 429
• Identity: 103/429 - (24%)
• Similarity: 164/429 - (38%)
• Gaps: 123/429 - (28%)

  Fly    25 VYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSSGT--PSKRGI 87
            |:|||.::::|::||.:||.||||||:|:|:|||||.||||.||:..:|:..:....  |.|||.
Human    10 VFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGP 74

  Fly    88 KKKEKEPDPEPESEEDEYTFTEND----------------VDTHQA---------------TTSS 121
            |.|......:.:::...|.|..:.                ..|.:|               |::|
Human    75 KPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRAREGLRNMGLSPPASSTSTS 139

  Fly   122 AT--------------HDKESKKEKKHHHHHHHHHHIKSERNSGRRSESPLTHHHHHHHHESKRQ 172
            :|              .|:|..:|::...........:.||.:.|..:.|
Human   140 STCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKP--------------- 189

  Fly   173 RIDHSSSSNSSFTHNSFVPEPDSNSSSSEDQPL------IGTKRKAEVLKE----SGKIGVTIKT 227
                ||..:||....   |:|.........:||      :|...|...|.:    :||.
Human   190 ----SSPGDSSKKRG---PKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGKF------ 241

  Fly   228 SPDGPTIKPQPTQQVTPSQQQPFQDQQQAE---KIASE-----------AATQLKSEQQATPLAT 278
             |.|.::.....:|.:...|........||   |:|.:           |..:.|.:....|..|
Human   242 -PAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGALDPNGT 305

  Fly   279 EAINTT--PAESGAEEEEVANEEGNQQAPQVPSENNNIPKPCNNLAINQKQPLTPLSPRALPPRF 341
            ...:.:  |:..|....::..:.|.      ||....||     :|.....|         ....
Human   306 RVRHGSGPPSSGGGLYRDMGAQGGR------PSLIARIP-----VARILGDP---------EEES 350

  Fly   342 WLPAKCNISNRVVITDVTVNLETVTIRECKTERGFFRER 380
            |.|:..|: .:||:||||.|..||||:|..|::|||:|:
Human   351 WSPSLTNL-EKVVVTDVTSNFLTVTIKESNTDQGFFKEK 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pc	NP_524199.1	CHROMO	25..77	CDD:214605	29/51 (57%)
CBX8	NP_065700.1	CHROMO	10..62	CDD:214605	29/51 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..241		22/138 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..327		4/28 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	71	1.000	Domainoid score	I9425
eggNOG	1	0.900	-	-		E1_KOG2748
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4722
Isobase	1	0.950	-	0	Normalized mean entropy	S6285
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41418
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46389
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2447
SonicParanoid	1	1.000	-	-		X2049
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	11.000