DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pc and Cbx4

DIOPT Version :9

Sequence 1:	NP_524199.1	Gene:	Pc / 40358	FlyBaseID:	FBgn0003042	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_008766707.2	Gene:	Cbx4 / 501403	RGDID:	1587243	Length:	551	Species:	Rattus norvegicus

Alignment Length:	358	Identity:	86/358 - (24%)
Similarity:	135/358 - (37%)	Gaps:	59/358 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSSGTPSKRGIKK 89
            |:|.|.|.:||::||.|||.|||:||:.:|||||||.||||.||:..::...:..   ...|.:|
  Rat    10 VFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQE---QLMGYRK 71

  Fly    90 KEKEPDP----EPESEEDEYTFT-------ENDVDTHQATTSSATHDKESKKEKKHHHHHHHHHH 143
            :..:|.|    .|.........|       :|.......|.......:.....||||.:..|
  Rat    72 RGPKPKPLVVQVPTFARRSNVLTGLQDSSADNRAKLELGTQGKGQGHQYELNSKKHHQYQPH--- 133

  Fly   144 IKSERN--------SGRRSESPLTHHHHHHHHESKRQRIDHSSSSNSSFTHNSFVPEPDSNSSSS 200
             ..||:        ||:......:..||.:..:.|...:.:..|...:       |.|......:
  Rat   134 -GKERSGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGSHKEA-------PSPTCPDLGA 190

  Fly   201 EDQP----LIGTKRK---AEVLKESGKIGVTIKTSPDGPT--IKPQPTQQVTPS----QQQPFQD 252
            :..|    ..|...|   ..|....|..|...|.|..||.  :.|.|.:.|..:    :.:..::
  Rat   191 KSHPPDKWAHGAAAKGYLGAVKPLGGGAGAPGKGSEKGPPNGLTPAPKEAVAGNGIGGKMKIVKN 255

  Fly   253 QQQAEKIASEAATQLKSEQQATPLATEAINTTPAESGAEEEEVANEEGNQQAPQV------PSEN 311
            :.:..:|....:..:::..||..:.:.....:.|.|.:.::..| ||.:.||.:.      .||.
  Rat   256 KNKNGRIVIVMSKYMENGMQAVKIKSGEAAESEARSPSHKKRAA-EERHPQADRTFKKAAGASEE 319

  Fly   312 NNIPKPCNN-----LAINQKQPLTPLSPRALPP 339
            .....||..     |.....|| ..|..|.|.|
  Rat   320 KKAEVPCKRREEEALVSGDPQP-QDLGSRKLSP 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pc	NP_524199.1	CHROMO	25..77	CDD:214605	29/51 (57%)
Cbx4	XP_008766707.2	CD_Cbx4	8..62	CDD:349292	29/51 (57%)
Cbx4	XP_008766707.2	CBX7_C	<529..550	CDD:407338
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	71	1.000	Domainoid score	I9195
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4621
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45533
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.060